Evidence map›Paper›PMID 34068145›Full record

ArticleMolecules (Basel, Switzerland)2021

Development of One-Step Non-Solvent Extraction and Sensitive UHPLC-MS/MS Method for Assessment of N-(n-Butyl) Thiophosphoric Triamide (NBPT) and N-(n-Butyl) Phosphoric Triamide (NBPTo) in Milk.

Chikere G Nkwonta, Macdara O'Neill, Niharika Rahman, Mary Moloney, Patrick J Forrestal, Sean A Hogan, Karl G Richards, Enda Cummins, Martin Danaher

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chikere G NkwontaFood Safety Department, Teagasc Food Research Centre, Ashtown, D15KN3K Dublin, Ireland.ORCID 0000-0002-0843-7894
Macdara O'NeillTeagasc, Johnstown Castle, Co., Y35 Y521 Wexford, Ireland.ORCID 0000-0003-0249-967X
Niharika RahmanTeagasc, Johnstown Castle, Co., Y35 Y521 Wexford, Ireland.ORCID 0000-0001-6029-7369
Mary MoloneyFood Safety Department, Teagasc Food Research Centre, Ashtown, D15KN3K Dublin, Ireland.
Patrick J ForrestalTeagasc, Johnstown Castle, Co., Y35 Y521 Wexford, Ireland.
Sean A HoganFood Chemistry and Technology Department, Teagasc Food Research Centre, Moorepark, Fermoy, Co. Cork, P61 C996 Cork, Ireland.
Karl G RichardsTeagasc, Johnstown Castle, Co., Y35 Y521 Wexford, Ireland.ORCID 0000-0002-3703-3450
Enda CumminsSchool of Biosystems and Food Engineering, Agriculture and Food Science, University College Dublin, D04 V1W8 Belfield, Ireland.
Martin DanaherFood Safety Department, Teagasc Food Research Centre, Ashtown, D15KN3K Dublin, Ireland.ORCID 0000-0003-4060-0441

Funding

Department of Agriculture, Food and the Marine, Ireland 17F207
6 · The paper itself

Abstract

N-(n-butyl) thiophosphoric triamide (NBPT) is a urease inhibitor utilised in urea-based fertilizers. In Ireland, fertilizer treated with NBPT is applied to pasture to mitigate both ammonia and nitrous oxide emissions, but concerns arise as to the potential for residues in milk products. A quick ultrafiltration extraction and ultra-high performance liquid chromatography coupled with mass spectrometry triple quadrupole (UHPLC-MS/MS) quantitation method was developed and validated in this study. The method was applied in the analysis of samples collected from a field study investigating potential transfer of NBPT residues into milk. NBPT and NBPTo residues, were extracted from fortified milk samples and analysed on a UHPLC-MS/MS with recoveries ranging from 74 to 114%. Validation of the UHPLC-MS/MS method at low (0.0020 mg kg

Indexed as

Tandem Mass SpectrometryAmidesAnimalsChromatography, High Pressure LiquidFarmsMilkOrganophosphorus CompoundsReproducibility of ResultsSolventsAmidesN-(n-butyl) phosphorictriamideN-(n-butyl) thiophosphoric triamideOrganophosphorus CompoundsSolventscattlemilkN-(n-butyl) phosphoric triamideN-(n-butyl) thiophosphoric triamideresiduestabilityUHPLC-MS/MSultrafiltration extractionurease inhibitor

Identifiers

PMID34068145
PMCPMC8153019

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.