Evidence map›Paper›PMID 34068033›Full record

ArticleInternational journal of molecular sciences2021

Molecular and Functional Characterization of MobK Protein-A Novel-Type Relaxase Involved in Mobilization for Conjugational Transfer of

Katarzyna Paulina Nowak, Agnieszka Sobolewska-Ruta, Agata Jagiełło, Anna Bierczyńska-Krzysik, Piotr Kierył, Paweł Wawrzyniak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Katarzyna Paulina NowakInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5a, 02-106 Warsaw, Poland.ORCID 0000-0003-1887-9984
Agnieszka Sobolewska-RutaDepartment of Biomedical Technology, Cosmetics Chemicals and Electrochemistry, Łukasiewicz Research Network-Industrial Chemistry Institute, Rydygiera 8, 01-793 Warsaw, Poland.
Agata JagiełłoDepartment of Biomedical Technology, Cosmetics Chemicals and Electrochemistry, Łukasiewicz Research Network-Industrial Chemistry Institute, Rydygiera 8, 01-793 Warsaw, Poland.ORCID 0000-0001-8489-7254
Anna Bierczyńska-KrzysikDepartment of Biomedical Technology, Cosmetics Chemicals and Electrochemistry, Łukasiewicz Research Network-Industrial Chemistry Institute, Rydygiera 8, 01-793 Warsaw, Poland.
Piotr KieryłDepartment of Biomedical Technology, Cosmetics Chemicals and Electrochemistry, Łukasiewicz Research Network-Industrial Chemistry Institute, Rydygiera 8, 01-793 Warsaw, Poland.
Paweł WawrzyniakInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5a, 02-106 Warsaw, Poland.ORCID 0000-0003-4348-3527
Łukasiewicz Research Network - Industrial Chemistry Institute · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conjugation, besides transformation and transduction, is one of the main mechanisms of horizontal transmission of genetic information among bacteria. Conjugational transfer, due to its essential role in shaping bacterial genomes and spreading of antibiotics resistance genes, has been widely studied for more than 70 years. However, new and intriguing facts concerning the molecular basis of this process are still being revealed. Most recently, a novel family of conjugative relaxases (Mob proteins) was distinguished. The characteristic feature of these proteins is that they are not related to any of Mobs described so far. Instead of this, they share significant similarity to tyrosine recombinases. In this study MobK-a tyrosine recombinase-like Mob protein, encoded by pIGRK cryptic plasmid from the

Indexed as

Conjugation, GeneticRecombination, GeneticBacterial ProteinsBase SequenceDNA, BacterialEndodeoxyribonucleasesKlebsiella pneumoniaePlasmidsBacterial ProteinsDNA, BacterialEndodeoxyribonucleasesconjugationG-quadruplexhorizontal gene transferKlebsiella pneumoniaeMobmobile genetic elementsMobKpIGRKrelaxasetyrosine recombinase

Identifiers

PMID34068033
PMCPMC8152469
OpenAlexW3160362674

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.