Evidence map›Paper›PMID 34068026›Full record

ArticleCancers2021

Comprehensive Assessment of Incidence, Risk Factors, and Mechanisms of Impaired Medical and Psychosocial Health Outcomes among Adolescents and Young Adults with Cancer: Protocol of the Prospective Observational COMPRAYA Cohort Study.

Olga Husson, Marjolijn J L Ligtenberg, Lonneke V van de Poll-Franse, Judith B Prins, Martin J van den Bent, Mies C van Eenbergen, Renske Fles, Eveliene Manten-Horst, Jourik A Gietema, Winette T A van der Graaf

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Adding home-use BIA scales, online food diaries, and tape-measures to large-scale questionnaire studies: Insights from the population-based PROFILES registry research.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Long-term health-related quality of life among adolescent and young adult breast cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Olga HussonDepartment of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-1387-8686
Marjolijn J L LigtenbergDepartment of Human Genetics, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0003-1290-1474
Lonneke V van de Poll-FranseDivision of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Judith B PrinsDepartment of Medical Psychology, Radboud Institute for Health Sciences, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0001-5720-6091
Martin J van den BentDepartment of Neurology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-5710-5127
Mies C van EenbergenResearch & Development, Netherlands Comprehensive Cancer Organization (IKNL), 3511 DT Utrecht, The Netherlands.ORCID 0000-0001-6731-3296
Renske FlesDepartment of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Eveliene Manten-HorstDutch AYA Care Network, 3511 DT Utrecht, The Netherlands.
Jourik A GietemaDepartment of Medical Oncology, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Winette T A van der GraafDepartment of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0001-7549-3338
Erasmus MC · NLRadboud University Nijmegen · NLInstitute of Cancer Research · GBNetherlands Comprehensive Cancer Organisation · NLThe Netherlands Cancer Institute · NLTilburg University · NLUniversity Medical Center Groningen · NL

Funding

KWF Kankerbestrijding 11788Nederlandse Organisatie voor Wetenschappelijk Onderzoek 198.007
6 · The paper itself

Abstract

Adolescent and young adult (AYA) cancer patients suffer from delay in diagnosis, and lack of centralized cancer care, age-adjusted expertise, and follow-up care. This group presents with a unique spectrum of cancers, distinct tumor biology, cancer risk factors, developmental challenges, and treatment regimens that differ from children and older adults. It is imperative for advances in the field of AYA oncology to pool data sources across institutions and create large cohorts to address the many pressing questions that remain unanswered in this vulnerable population. We will create a nationwide infrastructure (COMPRAYA) for research into the incidence, predictive/prognostic markers, and underlying mechanisms of medical and psychosocial outcomes for AYA between 18-39 years diagnosed with cancer. A prospective, observational cohort of (

Indexed as

adolescent and young adult oncologygenetic riskhealth-related quality of lifelate effectssurvival

Identifiers

PMID34068026
PMCPMC8152481
OpenAlexW3160220858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.