Evidence map›Paper›PMID 34067956›Full record

ArticleCancers2021

Small RNAs in Seminal Plasma as Novel Biomarkers for Germ Cell Tumors.

Nina Mørup, Rytis Stakaitis, Ieva Golubickaite, Meritxell Riera, Marlene Danner Dalgaard, Mikkel H Schierup, Niels Jørgensen, Gedske Daugaard, Anders Juul, Kristian Almstrup

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. The utility of cfDNA in TGCT patient management: a systematic review.Therapeutic advances in medical oncology · 2022
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Nina MørupDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-7332-4116
Rytis StakaitisDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-5946-1731
Ieva GolubickaiteDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0003-2739-8576
Meritxell RieraBioinformatics Research Centre, Aarhus University, 8000 Aarhus C, Denmark.
Marlene Danner DalgaardDTU Multi-Assay Core, Department of Health Technology, Technical University of Denmark, 2800 Lyngby, Denmark.
Mikkel H SchierupBioinformatics Research Centre, Aarhus University, 8000 Aarhus C, Denmark.ORCID 0000-0002-5028-1790
Niels JørgensenDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0003-4827-0838
Gedske DaugaardDepartment of Oncology, Copenhagen University Hospital, 2100 Copenhagen, Denmark.ORCID 0000-0002-9618-9180
Anders JuulDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Kristian AlmstrupDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-1832-0307
Copenhagen University Hospital · DKAarhus University · DKLithuanian University of Health Sciences · LTUniversity of Copenhagen · DKTechnical University of Denmark · DK

Funding

CSRD VA 1Dansk Kræftforsknings Fond FID1839672ReproUnion 20200407
6 · The paper itself

Abstract

Circulating miRNAs secreted by testicular germ cell tumors (TGCT) show great potential as novel non-invasive biomarkers for diagnosis of TGCT. Seminal plasma (SP) represents a biofluid closer to the primary site. Here, we investigate whether small RNAs in SP can be used to diagnose men with TGCTs or the precursor lesions, germ cell neoplasia in situ (GCNIS). Small RNAs isolated from SP from men with TGCTs (

Indexed as

diagnosticssmall RNAstesticular cancer

Identifiers

PMID34067956
PMCPMC8152278
OpenAlexW3163871149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.