Evidence map›Paper›PMID 34067934›Full record

ArticleSensors (Basel, Switzerland)2021

Classification of Diffuse Glioma Subtype from Clinical-Grade Pathological Images Using Deep Transfer Learning.

Sanghyuk Im, Jonghwan Hyeon, Eunyoung Rha, Janghyeon Lee, Ho-Jin Choi, Yuchae Jung, Tae-Jung Kim

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Dysregulation of inflammasome activation in glioma.Cell communication and signaling : CCS · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Artificial intelligence in neuro-oncology.Frontiers in neuroscience · 2023
    Review
  16. Article
  17. Review
  18. Review
  19. Brain Tumor Imaging: Applications of Artificial Intelligence.Seminars in ultrasound, CT, and MR · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sanghyuk ImDepartment of Neurosurgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Jonghwan HyeonSchool of Computing, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.
Eunyoung RhaDepartment of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Janghyeon LeeSchool of Computing, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.
Ho-Jin ChoiSchool of Computing, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.
Yuchae JungSchool of Computing, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID 0000-0003-2202-7303
Tae-Jung KimDepartment of Hospital Pathology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0003-3140-3681

Funding

Basic Science Research Program through the National 259 Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning 260 (MIST) 2017R1E1A1A01078335, 2018R1C1B6005381
6 · The paper itself

Abstract

Diffuse gliomas are the most common primary brain tumors and they vary considerably in their morphology, location, genetic alterations, and response to therapy. In 2016, the World Health Organization (WHO) provided new guidelines for making an integrated diagnosis that incorporates both morphologic and molecular features to diffuse gliomas. In this study, we demonstrate how deep learning approaches can be used for an automatic classification of glioma subtypes and grading using whole-slide images that were obtained from routine clinical practice. A deep transfer learning method using the ResNet50V2 model was trained to classify subtypes and grades of diffuse gliomas according to the WHO's new 2016 classification. The balanced accuracy of the diffuse glioma subtype classification model with majority voting was 0.8727. These results highlight an emerging role of deep learning in the future practice of pathologic diagnosis.

Indexed as

Brain NeoplasmsGliomaHumansMachine LearningMutationWorld Health Organizationconvolutional neural networkdeep transfer learningdigital pathologygliomaoligodendroglial tumor

Identifiers

PMID34067934
PMCPMC8156672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.