Evidence map›Paper›PMID 34067933›Full record

ArticleInternational journal of molecular sciences2021

Living-Cell Diffracted X-ray Tracking Analysis Confirmed Internal Salt Bridge Is Critical for Ligand-Induced Twisting Motion of Serotonin Receptors.

Kazuhiro Mio, Shoko Fujimura, Masaki Ishihara, Masahiro Kuramochi, Hiroshi Sekiguchi, Tai Kubo, Yuji C Sasaki

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Visualizing Intramolecular Dynamics of Membrane Proteins.International journal of molecular sciences · 2022
    Review
  8. Allosteric Modulators of G Protein-Coupled Receptors.International journal of molecular sciences · 2022
    Article
  9. Dynamic motions of ice-binding proteins in livingBiochemistry and biophysics reports · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kazuhiro MioAIST-UTokyo Advanced Operando-Measurement Technology Open Innovation Laboratory (OPERANDO-OIL), National Institute of Advanced Industrial Science and Technology (AIST), 6-2-3 Kashiwanoha, Chiba 277-0882, Japan.ORCID 0000-0002-1655-8231
Shoko FujimuraAIST-UTokyo Advanced Operando-Measurement Technology Open Innovation Laboratory (OPERANDO-OIL), National Institute of Advanced Industrial Science and Technology (AIST), 6-2-3 Kashiwanoha, Chiba 277-0882, Japan.
Masaki IshiharaAIST-UTokyo Advanced Operando-Measurement Technology Open Innovation Laboratory (OPERANDO-OIL), National Institute of Advanced Industrial Science and Technology (AIST), 6-2-3 Kashiwanoha, Chiba 277-0882, Japan.
Masahiro KuramochiAIST-UTokyo Advanced Operando-Measurement Technology Open Innovation Laboratory (OPERANDO-OIL), National Institute of Advanced Industrial Science and Technology (AIST), 6-2-3 Kashiwanoha, Chiba 277-0882, Japan.ORCID 0000-0003-1643-3997
Hiroshi SekiguchiCenter for Synchrotron Radiation Research, Japan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo-cho, Hyogo 679-5198, Japan.ORCID 0000-0001-7590-3624
Tai KuboAIST-UTokyo Advanced Operando-Measurement Technology Open Innovation Laboratory (OPERANDO-OIL), National Institute of Advanced Industrial Science and Technology (AIST), 6-2-3 Kashiwanoha, Chiba 277-0882, Japan.
Yuji C SasakiAIST-UTokyo Advanced Operando-Measurement Technology Open Innovation Laboratory (OPERANDO-OIL), National Institute of Advanced Industrial Science and Technology (AIST), 6-2-3 Kashiwanoha, Chiba 277-0882, Japan.ORCID 0000-0003-3403-237X
National Institute of Advanced Industrial Science and Technology · JPJapan Synchrotron Radiation Research Institute · JP

Funding

Japan Science and Technology Agency JP18071859Japan Society for the Promotion of Science JP17H05539, JP26102748, JP23591263
6 · The paper itself

Abstract

Serotonin receptors play important roles in neuronal excitation, emotion, platelet aggregation, and vasoconstriction. The serotonin receptor subtype 2A (5-HT

Indexed as

Carrier ProteinsCrystallography, X-RayGoldHEK293 CellsHumansIonsLigandsNanotechnologyReceptor, Serotonin, 5-HT2AReceptors, SerotoninSingle Molecule ImagingX-Ray DiffractionX-RaysCarrier ProteinsGoldIonsLigandsReceptor, Serotonin, 5-HT2AReceptors, Serotonin5-HT2A receptorGPCRintramolecular dynamicslive cellX-ray diffraction analysis

Identifiers

PMID34067933
PMCPMC8157010
OpenAlexW3161888270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.