Evidence map›Paper›PMID 34067874›Full record

ArticleBrain sciences2021

Developmental Language Disorder: Early Predictors, Age for the Diagnosis, and Diagnostic Tools. A Scoping Review.

Alessandra Sansavini, Maria Elena Favilla, Maria Teresa Guasti, Andrea Marini, Stefania Millepiedi, Maria Valeria Di Martino, Simona Vecchi, Nadia Battajon, Laura Bertolo, Olga Capirci and 18 more

Open access · goldAbstract readScoping Review
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
27.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 179 citations in OpenAlex.

  1. Low language capacity in childhood: A systematic review of prevalence estimates.International journal of language & communication disorders
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  8. Investigating parental perspectives of the enablers and barriers to communication with their preterm infants: A narrative study.Journal of child health care : for professionals working with children in the hospital and community · 2026
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 18 institutions in 1 country.

Alessandra SansaviniDepartment of Psychology "Renzo Canestrari", University of Bologna, Viale Berti Pichat 5, 40127 Bologna, Italy.ORCID 0000-0002-1991-9864
Maria Elena FavillaDepartment of Education and Human Sciences, University of Modena and Reggio Emilia, Viale Allegri 9, 42121 Reggio Emilia, Italy.
Maria Teresa GuastiDepartment of Psychology, University Milano-Bicocca, Piazza Ateneo Nuovo 1, 20121 Milano, Italy.ORCID 0000-0002-4470-4187
Andrea MariniDepartment of Language and Literatures, Communication, Education and Society, Università di Udine, Via Margreth, 3, 33100 Udine, Italy.ORCID 0000-0002-6058-3864
Stefania MillepiediDepartment of Mental Health, ATNO, Via Cocchi, 7/9, 56121 Pisa, Italy.
Maria Valeria Di MartinoHealth Professions Integrated Service, Azienda Ospedaliera dei Colli di Napoli, 80131 Napoli, Italy.
Simona VecchiDepartment of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154 Rome, Italy.
Nadia BattajonNeonatal Intensive Care Unit Mother and Child Department, Ca' Foncello Hospital, Via Sant'Ambrogio di Fiera, 37, 31100 Treviso, Italy.
Laura BertoloAIRIPA Associazione Italiana per la Ricerca e l'Intervento nella Psicopatologia dell'Apprendimento, Via Astichello, 10, 35135, Padova, Galleria G. Berchet, 3, 35131 Padova, Italy.
Olga CapirciInstitute of Cognitive Sciences and Technologies, National Research Council, Via Nomentana 56, 00161 Rome, Italy.
Barbara CarrettiDepartment of General Psychology, University of Padova, Via Venezia 8, 35131 Padova, Italy.ORCID 0000-0001-5147-7544
Maria Paola ColateiDepartment of Clinical Medicine, Public Health, Life and Environmental Sciences, University of L'Aquila, Palazzo Camponeschi, Piazza Santa Margherita 2, 67100 L'Aquila, Italy.
Cristina FrioniStudio di Psicoterapia e Riabilitazione dell'età evolutiva, Via Annone 1, 00199 Roma, Italy.
Luigi MarottaDepartment of Intensive and Robotic Neurorehabilitation, IRCCS Bambino Gesù Children's Hospital, Lungomare Marconi 36, 00058 S. Marinella, Roma, Italy.
Sara MassaAzienda Usl Toscana Centro, Piazza Santa Maria Nuova 1, 50121 Firenze, Italy.
Letizia MichelazzoFederazione Logopedisti Italiani, Via Daniello Bartoli, 00152 Roma, Italy.
Chiara PeciniDepartment of Education, Languages, Intercultures, Literatures and Psychology, University of Florence, Complesso di San Salvi, Padiglione 26, Via di San Salvi 12, 50135 Firenze, Italy.ORCID 0000-0002-7857-7884
Silvia PiazzalungaDepartment of Biomedical and Clinical Sciences "L. Sacco", Università degli Studi di Milano, Via G.B.Grassi, 74, 20157 Milano, Italy.
Manuela PierettiFederazione Logopedisti Italiani, Via Daniello Bartoli, 00152 Roma, Italy.
Pasquale RinaldiInstitute of Cognitive Sciences and Technologies, National Research Council, Via Nomentana 56, 00161 Rome, Italy.ORCID 0000-0002-6544-7941
Renata SalvadoriniUO Neurology and Neurorehabilitation, IRCCS Stella Maris Foundation, Viale del Tirreno 331, 56128 Calambrone, Italy.
Cristiano TermineDepartment of Medicine and Surgery, University of Insubria, Via Ravasi 2, 21100 Varese, Italy.
Mariagrazia ZuccariniDepartment of Psychology "Renzo Canestrari", University of Bologna, Viale Berti Pichat 5, 40127 Bologna, Italy.
Simonetta D'AmicoCLASTA-Communication & Language Acquisition Studies in Typical & Atypical Population, Piazza Epiro 12D, 00183 Roma, Italy.
Anna Giulia De CagnoFederazione Logopedisti Italiani, Via Daniello Bartoli, 00152 Roma, Italy.
Maria Chiara LevoratoCLASTA-Communication & Language Acquisition Studies in Typical & Atypical Population, Piazza Epiro 12D, 00183 Roma, Italy.
Tiziana RossettoFederazione Logopedisti Italiani, Via Daniello Bartoli, 00152 Roma, Italy.
Maria Luisa LorussoDepartment of Child Psychopathology, Scientific Institute IRCCS E. Medea, Via Don Luigi Monza 20, 23842 Bosisio Parini, Italy.ORCID 0000-0003-4640-306X
National Research Council · ITUniversity of Bologna · ITUniversity of L'Aquila · ITUniversity of Padua · ITAgenzia Regionale Parchi · ITAzienda Usl Toscana Centro · ITBambino Gesù Children's Hospital · ITCa' Foncello Hospital · ITFondazione Roma · ITFondazione Stella Maris · ITIRCCS Eugenio Medea · ITItalian Association for Cancer Research · ITUniversity of Florence · ITUniversity of Insubria · ITUniversity of Milan · ITUniversity of Milano-Bicocca · ITUniversity of Modena and Reggio Emilia · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDevelopmental Language Disorder (DLD) is frequent in childhood and may have long-term sequelae. By employing an evidence-based approach, this scoping review aims at identifying (a) early predictors of DLD; (b) the optimal age range for the use of screening and diagnostic tools; (c) effective diagnostic tools in preschool children.

methodsWe considered systematic reviews, meta-analyses, and primary observational studies with control groups on predictive, sensitivity and specificity values of screening and diagnostic tools and psycholinguistic measures for the assessment of DLD in preschool children. We identified 37 studies, consisting of 10 systematic reviews and 27 primary studies.

resultsDelay in gesture production, receptive and/or expressive vocabulary, syntactic comprehension, or word combination up to 30 months emerged as early predictors of DLD, a family history of DLD appeared to be a major risk factor, and low socioeconomic status and environmental input were reported as risk factors with lower predictive power. Optimal time for screening is suggested between age 2 and 3, for diagnosis around age 4. Because of the high variability of sensitivity and specificity values, joint use of standardized and psycholinguistic measures is suggested to increase diagnostic accuracy.

conclusionsMonitoring risk situations and employing caregivers' reports, clinical assessment and multiple linguistic measures are fundamental for an early identification of DLD and timely interventions.

Indexed as

age of assessmentdevelopmental language disorderdiagnostic toolsearly predictorsevidence-based medicinelanguage delaylate talkersscreening tools

Identifiers

PMID34067874
PMCPMC8156743
OpenAlexW3163121887

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.