Evidence map›Paper›PMID 34067830›Full record

ArticleJournal of clinical medicine2021

Targeting Alcohol Septal Ablation in Patients with Obstructive Hypertrophic Cardiomyopathy Candidates for Surgical Myectomy: Added Value of Three-Dimensional Intracoronary Myocardial Contrast Echocardiography.

Giovanni La Canna, Iside Scarfò, Irina Arendar, Antonio Colombo, Lucia Torracca, Davide Margonato, Matteo Montorfano, Ottavio Alfieri

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Giovanni La CannaApplied Diagnostic Echocardiography Unit, IRCCS Humanitas Clinical and Research Center, 20089 Rozzano, Italy.
Iside ScarfòApplied Diagnostic Echocardiography Unit, IRCCS Humanitas Clinical and Research Center, 20089 Rozzano, Italy.
Irina ArendarApplied Diagnostic Echocardiography Unit, IRCCS Humanitas Clinical and Research Center, 20089 Rozzano, Italy.
Antonio ColomboInterventional Cardiology Unit, IRCCS Humanitas Clinical and Research Center, 20089 Rozzano, Italy.
Lucia TorraccaCardiac Surgery, IRCCS Humanitas Clinical and Research Center, 20089 Rozzano, Italy.
Davide MargonatoInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Matteo MontorfanoInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Ottavio AlfieriCardiac Surgery Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Humanitas University · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITVita-Salute San Raffaele University · ITIstituto di Ricovero e Cura a Carattere Scientifico San Raffaele

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyocardial contrast two-dimensional echocardiography (MC-2DE) is widely used to address alcohol septal ablation (ASA) in obstructive hypertrophic cardiomyopathy (HCM). Owing to its limited cut-planes, MC-2DE may inaccurately identify the contrast misplacement associated with an unsuccessful or complicated ASA outcome.

objectiveThe aim of this study was to assess the added value of myocardial contrast three-dimensional echocardiography (MC-3DE) compared with MC-2DE to identify the appropriate matching between the target septal zone (TSZ) and coronary artery branch for safe and long-term effective ASA in HCM patients.

methodsA consecutive series of 52 symptomatic obstructive HCM patients referred for isolated surgical myectomy (SM) was analyzed with MC-2DE and MC-3DE following injection of echocontrast into one or more septal branches. MC-2DE and MC-3DE patterns were categorized according to complete (

resultsMC-2DE per patient analysis showed a

conclusionsRefining high risk or life-threatening contrast misplacement, MC-3DE is more accurate than conventional MC-2DE to target safe and long-term effective septal reduction with ASA in obstructive HCM patients referred for isolated SM.

Indexed as

alcohol septal ablationhypertrophic cardiomyopathyleft ventricular obstructionmyocardial contrast echocardiographysurgical myectomythree-dimensional echocardiography

Identifiers

PMID34067830
PMCPMC8156226
OpenAlexW3160530296

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.