Evidence map›Paper›PMID 34067753›Full record

ReviewGenes2021

Regeneration Potential of Jellyfish: Cellular Mechanisms and Molecular Insights.

Sosuke Fujita, Erina Kuranaga, Yu-Ichiro Nakajima

Abstract readReview
In one paragraph

Review in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Microrna Expression inMicroRNA (Shariqah, United Arab Emirates) · 2026
    Article
  4. Article
  5. Regeneration and Musculature in HalvedIntegrative organismal biology (Oxford, England) · 2025
    Article
  6. Article
  7. The mitochondrial genome of an invasive hydromedusa:Mitochondrial DNA. Part B, Resources · 2025
    Article
  8. Homosalate and ERK Knockdown in the Modulation ofCurrent issues in molecular biology · 2024
    Article
  9. Extraordinary model systems for regeneration.Development (Cambridge, England) · 2024
    Article
  10. Article
  11. Article
  12. The salamander blastema within the broader context of metazoan regeneration.Frontiers in cell and developmental biology · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sosuke FujitaGraduate School of Life Sciences, Tohoku University, Sendai 980-8578, Miyagi, Japan.
Erina KuranagaGraduate School of Life Sciences, Tohoku University, Sendai 980-8578, Miyagi, Japan.ORCID 0000-0001-6300-2087
Yu-Ichiro NakajimaGraduate School of Life Sciences, Tohoku University, Sendai 980-8578, Miyagi, Japan.ORCID 0000-0002-1823-5989

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medusozoans, the Cnidarian subphylum, have multiple life stages including sessile polyps and free-swimming medusae or jellyfish, which are typically bell-shaped gelatinous zooplanktons that exhibit diverse morphologies. Despite having a relatively complex body structure with well-developed muscles and nervous systems, the adult medusa stage maintains a high regenerative ability that enables organ regeneration as well as whole body reconstitution from the part of the body. This remarkable regeneration potential of jellyfish has long been acknowledged in different species; however, recent studies have begun dissecting the exact processes underpinning regeneration events. In this article, we introduce the current understanding of regeneration mechanisms in medusae, particularly focusing on cellular behaviors during regeneration such as wound healing, blastema formation by stem/progenitor cells or cell fate plasticity, and the organism-level patterning that restores radial symmetry. We also discuss putative molecular mechanisms involved in regeneration processes and introduce a variety of novel model jellyfish species in the effort to understand common principles and diverse mechanisms underlying the regeneration of complex organs and the entire body.

Indexed as

RegenerationAnimalsBody PatterningCell DifferentiationCnidariaStem Cellsdedifferentiationjellyfishmedusapatterningradial symmetryregenerationstem/progenitor cellstransdifferentiationwound healing

Identifiers

PMID34067753
PMCPMC8156412

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.