Evidence map›Paper›PMID 34067705›Full record

ArticleBiomolecules2021

Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic

Kehong Zhang, Simona Pace, Paul M Jordan, Lukas K Peltner, Alexander Weber, Dagmar Fischer, Robert K Hofstetter, Xinchun Chen, Oliver Werz

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. A comprehensive review ofFrontiers in pharmacology · 2023
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Kehong ZhangDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University, Philosophenweg 14, 07743 Jena, Germany.
Simona PaceDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University, Philosophenweg 14, 07743 Jena, Germany.
Paul M JordanDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University, Philosophenweg 14, 07743 Jena, Germany.
Lukas K PeltnerDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University, Philosophenweg 14, 07743 Jena, Germany.ORCID 0000-0003-3895-4558
Alexander WeberDepartment of Chemistry and Pharmacy, Pharmaceutical Technology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Cauerstrasse 4, 91058 Erlangen, Germany.
Dagmar FischerDepartment of Chemistry and Pharmacy, Pharmaceutical Technology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Cauerstrasse 4, 91058 Erlangen, Germany.
Robert K HofstetterDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University, Philosophenweg 14, 07743 Jena, Germany.
Xinchun ChenGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Pathogen Biology, Shenzhen University School of Medicine, Shenzhen 518000, China.
Oliver WerzDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University, Philosophenweg 14, 07743 Jena, Germany.ORCID 0000-0002-5064-4379
Friedrich Schiller University Jena · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEShenzhen University · CN

Funding

Deutsche Forschungsgemeinschaft SFB1127Deutsche Forschungsgemeinschaft SFB1278European Social Fund 2019 FGR 0095
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

A549 CellsAntirheumatic AgentsArachidonate 5-LipoxygenaseChromatography, High Pressure LiquidGene Expression RegulationGlycosidesHumansImmunity, InnateLipidomicsMacrophagesProstaglandin-Endoperoxide SynthasesProstaglandinsTandem Mass SpectrometryThromboxanesTripterygiumALOX5 protein, humanAntirheumatic AgentsArachidonate 5-LipoxygenaseGlycosidesProstaglandin-Endoperoxide SynthasesProstaglandinsThromboxanescyclooxygenaseinflammationlipoxygenasespecialized pro-resolving mediatorsTripterygium wilfordii glycosides

Identifiers

PMID34067705
PMCPMC8155965
OpenAlexW3162117667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.