Evidence map›Paper›PMID 34067685›Full record

ArticleBiomolecules2021

Antimicrobial Activity of Cyclic-Monomeric and Dimeric Derivatives of the Snail-Derived Peptide Cm-p5 against Viral and Multidrug-Resistant Bacterial Strains.

Melaine González-García, Fidel Morales-Vicente, Erbio Díaz Pico, Hilda Garay, Daniel G Rivera, Mark Grieshober, Lia Raluca Olari, Rüdiger Groß, Carina Conzelmann, Franziska Krüger and 14 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  6. Article
  7. Cm-p5 Peptide Dimers Inhibit Biofilms ofInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 6 institutions in 4 countries.

Melaine González-GarcíaCenter for Protein Studies, Faculty of Biology, University of Havana, 25 St, La Habana 10400, Cuba.
Fidel Morales-VicenteGeneral Chemistry Department, Faculty of Chemistry and Center for Natural Products Research, Faculty of Chemistry, University of Havana, Zapata street, La Habana 10400, Cuba.
Erbio Díaz PicoSynthetic Peptides Group, Center for Genetic Engineering and Biotechnology, P.O. Box 6162, La Habana 10600, Cuba.
Hilda GaraySynthetic Peptides Group, Center for Genetic Engineering and Biotechnology, P.O. Box 6162, La Habana 10600, Cuba.
Daniel G RiveraFaculty of Chemistry, Havana University, Zapata Street, La Habana 10400, Cuba.
Mark GrieshoberInstitute of Medical Microbiology and Hygiene, University Clinic of Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
Lia Raluca OlariInstitute of Molecular Virology, University Clinic of Ulm, Meyerhofstrasse. 1, 89081 Ulm, Germany.
Rüdiger GroßInstitute of Molecular Virology, University Clinic of Ulm, Meyerhofstrasse. 1, 89081 Ulm, Germany.ORCID 0000-0003-0355-7915
Carina ConzelmannInstitute of Molecular Virology, University Clinic of Ulm, Meyerhofstrasse. 1, 89081 Ulm, Germany.
Franziska KrügerInstitute of Molecular Virology, University Clinic of Ulm, Meyerhofstrasse. 1, 89081 Ulm, Germany.
Fabian ZechInstitute of Molecular Virology, University Clinic of Ulm, Meyerhofstrasse. 1, 89081 Ulm, Germany.
Caterina Prelli BozzoInstitute of Molecular Virology, University Clinic of Ulm, Meyerhofstrasse. 1, 89081 Ulm, Germany.
Janis A MüllerInstitute of Molecular Virology, University Clinic of Ulm, Meyerhofstrasse. 1, 89081 Ulm, Germany.
Alexander ZelikinDepartment of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus, Denmark.
Heinz RaberInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.
Dennis KubiczekInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.
Frank RosenauInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-9297-6419
Jan MünchInstitute of Molecular Virology, University Clinic of Ulm, Meyerhofstrasse. 1, 89081 Ulm, Germany.ORCID 0000-0001-7316-7141
Steffen StengerInstitute of Medical Microbiology and Hygiene, University Clinic of Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
Barbara SpellerbergInstitute of Medical Microbiology and Hygiene, University Clinic of Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
Octavio L FrancoDepartment of Biotechnology, Catholic University Dom Bosco, Campo Grande and Center for Biochemical and Proteomics Analyses, Catholic University of Brasilia, Brasilia, DF 71966-700, Brazil.ORCID 0000-0001-9546-0525
Armando A Rodriguez AlfonsoCore Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0001-5921-3770
Ludger StändkerCore Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-8436-4260
Anselmo J Otero-GonzalezCenter for Protein Studies, Faculty of Biology, University of Havana, 25 St, La Habana 10400, Cuba.
Universität Ulm · DEUniversity of Havana · CUInstitute of Medical Microbiology and Hygiene · DECentro de Ingeniería Genética y Biotecnología · CUAarhus University · DKUniversidade Católica de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cm-p5 is a snail-derived antimicrobial peptide, which demonstrated antifungal activity against the pathogenic strains of

Indexed as

Amino Acid SequenceAnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntiviral AgentsCandida albicansCell LineCell SurvivalDimerizationDrug Resistance, Multiple, BacterialGram-Negative BacteriaGram-Positive BacteriaHerpesvirus 2, HumanHumansMicrobial Sensitivity TestsSARS-CoV-2Anti-Bacterial AgentsAntimicrobial Cationic PeptidesAntiviral Agentsantibacterial activityantimicrobial peptideschemical derivativesCm-p5multiresistant microorganisms

Identifiers

PMID34067685
PMCPMC8156702
OpenAlexW3160414492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.