Evidence map›Paper›PMID 34067558›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Insight on the Structure-to-Activity of Carbosilane Metallodendrimers in the Fight against

Celia Llamazares, Natalia Sanz Del Olmo, Juan Soliveri, F Javier de la Mata, José Luis Copa-Patiño, Sandra García-Gallego

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. The repertoire of iron superoxide dismutases fromJournal of enzyme inhibition and medicinal chemistry · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Celia LlamazaresUniversity of Alcala, Department of Biomedicine and Biotechnology, 28805 Madrid, Spain.
Natalia Sanz Del OlmoUniversity of Alcala, Research Institute in Chemistry "Andrés M. del Río" (IQAR) and Faculty of Science, Department of Organic and Inorganic Chemistry, 28805 Madrid, Spain.
Juan SoliveriUniversity of Alcala, Department of Biomedicine and Biotechnology, 28805 Madrid, Spain.
F Javier de la MataUniversity of Alcala, Research Institute in Chemistry "Andrés M. del Río" (IQAR) and Faculty of Science, Department of Organic and Inorganic Chemistry, 28805 Madrid, Spain.ORCID 0000-0003-0418-3935
José Luis Copa-PatiñoUniversity of Alcala, Department of Biomedicine and Biotechnology, 28805 Madrid, Spain.ORCID 0000-0002-2162-3907
Sandra García-GallegoUniversity of Alcala, Research Institute in Chemistry "Andrés M. del Río" (IQAR) and Faculty of Science, Department of Organic and Inorganic Chemistry, 28805 Madrid, Spain.
Universidad de Alcalá · ES

Funding

Comunidad de Madrid IMMUNOTHERCAN-CM B2017/BMD-3733Comunidad de Madrid NANODENDMED-II B2017/BMD-3703Comunidad de Madrid Research Talent Attraction Program 2017-T2/IND-5243Comunidad de Madrid and University of Alcala Project CM/BG/2021-001Instituto de Salud Carlos III CIBER-BBNJunta de Comunidades de Castilla-La Mancha SBPLY/17/180501/000358Ministerio de Economía y Competitividad CTQ2017-86224-PSpanish Ministry of Universities Beatriz Galindo grant BG20/00231
6 · The paper itself

Abstract

Biofilm formation is a critical health concern, involved in most human bacterial infections. Combatting this mechanism, which increases resistance to traditional antibiotics and host immune defences, requires novel therapeutic approaches. The remarkable biocide activity and the monodispersity of carbosilane metallodendrimers make them excellent platforms to evaluate the impact of different structural parameters on the biological activity. In this work, we explore the influence of iminopyridine ring substituents on the antibacterial activity against planktonic and biofilm

Indexed as

antibacterialbiofilmcopperdendrimermetalmetallodendrimerrutheniumStaphylococcus aureus

Identifiers

PMID34067558
PMCPMC8156651
OpenAlexW3162090803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.