Evidence map›Paper›PMID 34067346›Full record

ArticleInternational journal of molecular sciences2021

Prenylated Flavonoids with Potential Antimicrobial Activity: Synthesis, Biological Activity, and In Silico Study.

Mauricio Osorio, Marcela Carvajal, Alejandra Vergara, Estefania Butassi, Susana Zacchino, Carolina Mascayano, Margarita Montoya, Sophia Mejías, Marcelo Cortez-San Martín, Yesseny Vásquez-Martínez

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Phytochemistry and Pharmacological Potential of the GenusPharmaceuticals (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. A FungalJournal of agricultural and food chemistry · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
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  14. Article
  15. Article
  16. Article
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  19. Article
  20. Stilbenoids and Flavonoids fromMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Mauricio OsorioLaboratorio de Productos Naturales, Departamento de Química, Universidad Técnica Federico Santa María, Valparaíso 2390123, Chile.
Marcela CarvajalCentro de Biotecnología CB-DAL, Universidad Técnica Federico Santa María, Valparaíso 2390136, Chile.
Alejandra VergaraCentro de Biotecnología CB-DAL, Universidad Técnica Federico Santa María, Valparaíso 2390136, Chile.
Estefania ButassiFarmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario 2000, Argentina.
Susana ZacchinoFarmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario 2000, Argentina.
Carolina MascayanoDepartamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.
Margarita MontoyaLaboratorio Bioquímica Celular, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.ORCID 0000-0002-6268-1118
Sophia MejíasLaboratorio Bioquímica Celular, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.
Marcelo Cortez-San MartínLaboratorio de Virología Molecular y Control de Patógenos, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.
Yesseny Vásquez-MartínezPrograma Centro de Investigaciones Biomédicas Aplicadas, Escuela de Medicina, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Santiago 9170022, Chile.
Universidad de Santiago de Chile · CLFederico Santa María Technical University · CLNational University of Rosario · AR

Funding

Consejo Nacional de Innovación, Ciencia y Tecnología 1130924Universidad de Santiago de Chile DICYT-USACH 021641MCUniversidad de Santiago de Chile DICYT-USACH 021901VM
6 · The paper itself

Abstract

Prenylated flavonoids are an important class of naturally occurring flavonoids with important biological activity, but their low abundance in nature limits their application in medicines. Here, we showed the hemisynthesis and the determination of various biological activities of seven prenylated flavonoids, named

Indexed as

AnimalsAnti-Bacterial AgentsATP-Binding Cassette TransportersCell LineCell Line, TumorComputer SimulationFlavanonesFlavonoidsFungiHumansIsoflavonesMiceMicrobial Sensitivity TestsPrenylationReactive Oxygen SpeciesStaphylococcus aureusAnti-Bacterial AgentsATP-Binding Cassette TransportersFlavanonesFlavonoidsIsoflavonesReactive Oxygen SpeciesantibacterialantifungalMRSAprenylated flavonoidssynergismsynthesis

Identifiers

PMID34067346
PMCPMC8196815
OpenAlexW3164212863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.