Evidence map›Paper›PMID 34067337›Full record

ArticlePathogens (Basel, Switzerland)2021

Identification of an Attenuated Substrain of

Julie A Lovchik, Douglas S Reed, Julie A Hutt, Fangfang Xia, Rick L Stevens, Thero Modise, Eileen M Barry, Terry H Wu

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Frontiers in microbiology · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julie A LovchikCenter for Infectious Disease & Immunity and Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
Douglas S ReedCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0003-0076-9023
Julie A HuttLovelace Respiratory Research Institute, Albuquerque, NM 87108, USA.
Fangfang XiaData Science and Learning, Argonne National Laboratory, Argonne, IL 60439, USA.ORCID 0000-0001-6567-0564
Rick L StevensComputing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA.
Thero ModiseDepartment of Biomedical Sciences, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Eileen M BarryCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Terry H WuCenter for Infectious Disease & Immunity and Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.ORCID 0000-0002-1667-1349

Funding

Advancement of New Live Attenuated F. Tularensis Type A Vaccine StrainsU01AI077909 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BARRY, EILEEN M. · 2009 to 2010
$1.1M
Immune response to inhalation of live attenuated vaccine in an outbred tularemia model (Resubmission)R21AI151268 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REED, DOUGLAS SCOTT · 2021 to 2022
$405k
National Institute of Allergy and Infectious Diseases HHSN272201000037I-HHSN27200001; HHSN272201400027C; U01 AI077909-01; 1 R01 AI123129-01NIAID NIH HHS R21 AI151268
6 · The paper itself

Abstract

Pneumonic tularemia is a highly debilitating and potentially fatal disease caused by inhalation of

Indexed as

attenuationFrancisella tularensisrabbitsratsSCHU S4substrainvirulence

Identifiers

PMID34067337
PMCPMC8224608

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.