Evidence map›Paper›PMID 34067304›Full record

ArticleInternational journal of molecular sciences2021

Exposure to the Methylselenol Precursor Dimethyldiselenide Induces a Reductive Endoplasmic Reticulum Stress in

Marc Dauplais, Pierre Mahou, Pierre Plateau, Myriam Lazard

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Does atmospheric dimethyldiselenide play a role in reducing COVID-19 mortality?Gondwana research : international geoscience journal · 2023
    Article
  3. Review
  4. Article
  5. Article
  6. THE MAIN CYTOTOXIC EFFECTS OF METHYLSELENINIC ACID ON VARIOUS CANCER CELLS.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marc DauplaisLaboratoire de Biologie Structurale de la Cellule, BIOC, École Polytechnique, CNRS-UMR7654, IP Paris, 91128 Palaiseau, France.ORCID 0000-0001-9599-1860
Pierre MahouLaboratoire d'Optique et Biosciences, École Polytechnique, CNRS UMR7645-INSERM U1182, IP Paris, 91128 Palaiseau, France.
Pierre PlateauLaboratoire de Biologie Structurale de la Cellule, BIOC, École Polytechnique, CNRS-UMR7654, IP Paris, 91128 Palaiseau, France.
Myriam LazardLaboratoire de Biologie Structurale de la Cellule, BIOC, École Polytechnique, CNRS-UMR7654, IP Paris, 91128 Palaiseau, France.ORCID 0000-0002-7154-1352
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylselenol (MeSeH) is a major cytotoxic metabolite of selenium, causing apoptosis in cancer cells through mechanisms that remain to be fully established. Previously, we demonstrated that, in

Indexed as

Endoplasmic ReticulumEndoplasmic Reticulum StressMethanolMolecular ChaperonesOrganoselenium CompoundsOxidation-ReductionProtein FoldingSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsUnfolded Protein ResponsedimethyldiselenidemethaneselenolMethanolMolecular ChaperonesOrganoselenium CompoundsSaccharomyces cerevisiae Proteinsdimethyldiselenidedisulfide bond formationER stressmethylselenoloxidative foldingreductive stressseleniumunfolded protein response

Identifiers

PMID34067304
PMCPMC8196827
OpenAlexW3165734754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.