Evidence map›Paper›PMID 34067214›Full record

ReviewCancers2021

Differentiated Thyroid Cancer: A Health Economic Review.

Klaas Van Den Heede, Neil S Tolley, Aimee N Di Marco, Fausto F Palazzo

Registry-linked trialAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05117853 (The Use of Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Total Thyroidectomy), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05117853 phase3unknown statusnot on this map

The Use of Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Total Thyroidectomy: A Randomized Clinical Trial

TypeinterventionalSponsorOnze Lieve Vrouw HospitalRan2021 to 2025Enrolled300ConditionsThyroid Disease, Hypoparathyroidism PostproceduralArmsAutofluorescent detection + Injection of indocyanine green, Gold standard of visual identification and evaluation of viability of the parathyroid glands.
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Thyroid surgery in the elderly: a surgical cohort.Langenbeck's archives of surgery · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Klaas Van Den HeedeDepartment of Endocrine & Thyroid Surgery, Hammersmith Hospital, London W12 0HS, UK.
Neil S TolleyDepartment of Endocrine & Thyroid Surgery, Hammersmith Hospital, London W12 0HS, UK.
Aimee N Di MarcoDepartment of Endocrine & Thyroid Surgery, Hammersmith Hospital, London W12 0HS, UK.ORCID 0000-0002-0079-1194
Fausto F PalazzoDepartment of Endocrine & Thyroid Surgery, Hammersmith Hospital, London W12 0HS, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of differentiated thyroid cancer (DTC) is rising, mainly because of an increased detection of asymptomatic thyroid nodularity revealed by the liberal use of thyroid ultrasound. This review aims to reflect on the health economic considerations associated with the increasing diagnosis and treatment of DTC. Overdiagnosis and the resulting overtreatment have led to more surgical procedures, increasing health care and patients' costs, and a large pool of community-dwelling thyroid cancer follow-up patients. Additionally, the cost of thyroid surgery seems to increase year on year even when inflation is taken into account. The increased healthcare costs and spending have placed significant pressure to identify potential factors associated with these increased costs. Some truly ground-breaking work in health economics has been undertaken, but more cost-effectiveness studies and micro-cost analyses are required to evaluate expenses and guide future solutions.

Indexed as

cost-benefit analysiseconomicsmedicalthyroid neoplasms

Identifiers

PMID34067214
PMCPMC8125846

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.