Evidence map›Paper›PMID 34067170›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Diagnostic Challenges in Epithelioid Pleural Mesothelioma: Case Series with Support from Electron Microscopy.

Francesco Fortarezza, Mila Della Barbera, Federica Pezzuto, Francesca Lunardi, Eleonora Faccioli, Giulia Pasello, Federico Rea, Stefania Rizzo, Fiorella Calabrese

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Deciduosis in a cesarean scar.Autopsy & case reports · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Francesco FortarezzaDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, Cardiovascular Pathology Unit, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-8954-5888
Mila Della BarberaDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, Cardiovascular Pathology Unit, University of Padova, 35128 Padova, Italy.
Federica PezzutoDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, Cardiovascular Pathology Unit, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-8023-3108
Francesca LunardiDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, Cardiovascular Pathology Unit, University of Padova, 35128 Padova, Italy.
Eleonora FaccioliDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, Thoracic Surgery Unit, University of Padova, 35128 Padova, Italy.
Giulia PaselloMedical Oncology 2, Istituto Oncologico Veneto IRCCS, 35128 Padova, Italy.
Federico ReaDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, Thoracic Surgery Unit, University of Padova, 35128 Padova, Italy.
Stefania RizzoDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, Cardiovascular Pathology Unit, University of Padova, 35128 Padova, Italy.
Fiorella CalabreseDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, Cardiovascular Pathology Unit, University of Padova, 35128 Padova, Italy.
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The histological diagnosis of pleural epithelioid mesothelioma can be difficult in the case of rare variants or in the definition of neoplasm origin in patients with previous or concomitant tumours. Currently, several immunohistochemical reactions are available in the surgical pathologist's armamentarium that allow us to obtain a more sensitive and specific diagnosis of malignant pleural mesothelioma. However, in some cases, the final interpretation remains inconclusive. Historically, ultrastructural examination has represented a useful tool for the definition of the mesothelial nature of neoplastic cells due to their peculiar morphological characteristics. The recent international guidelines for pathological diagnosis of pleural mesothelioma suggest the use of electron microscopy when the immunohistochemical reactions are equivocal or when further support of a diagnosis of mesothelioma is needed. This paper presents three cases of pleural epithelioid mesothelioma whose diagnoses were finally supported by ultrastructural examination.

Indexed as

histologyimmunohistochemistrymesotheliomatransmission electron microscopy

Identifiers

PMID34067170
PMCPMC8150908
OpenAlexW3158715320

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.