Evidence map›Paper›PMID 34067093›Full record

ArticleCells2021

Impact of the Uncoupling Protein 1 on Cardiovascular Risk in Patients with Rheumatoid Arthritis.

Lovisa I Lyngfelt, Malin C Erlandsson, Mitra Nadali, Shahram Hedjazifar, Rille Pullerits, Karin M Andersson, Petra Brembeck, Sofia Töyrä Silfverswärd, Ulf Smith, Maria I Bokarewa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lovisa I LyngfeltDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Malin C ErlandssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0003-1100-7577
Mitra NadaliDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Shahram HedjazifarLundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Rille PulleritsDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0002-5383-9817
Karin M AnderssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Petra BrembeckLundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Sofia Töyrä SilfverswärdDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0002-6641-2759
Ulf SmithLundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Maria I BokarewaDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0001-9424-5145
University of Gothenburg · SESahlgrenska University Hospital · SE

Funding

Swedish Association against Rheumatism R-477321Swedish Association against Rheumatism R-566961Swedish Research Council 521-2014-02637Swedish Research Council 521-2017-03025
6 · The paper itself

Abstract

Adiposity is strongly associated with cardiovascular (CV) morbidity. Uncoupling protein 1 (UCP1) increases energy expenditure in adipocytes and may counteract adiposity. Our objective was to investigate a connection between

Indexed as

Gene Expression RegulationAgedArthritis, RheumatoidBiomarkersCardiovascular DiseasesFemaleFollow-Up StudiesHumansInterleukin-6Middle AgedPrognosisProspective StudiesRisk FactorsUncoupling Protein 1BiomarkersIL6 protein, humanInterleukin-6UCP1 protein, humanUncoupling Protein 1adipose tissuecardiovascular riskIL-6rheumatoid arthritistocilizumabUCP-1

Identifiers

PMID34067093
PMCPMC8151725
OpenAlexW3159350077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.