Evidence map›Paper›PMID 34067082›Full record

ArticleInternational journal of molecular sciences2021

Analysis of Biomechanical Parameters of Muscle Soleus Contraction and Blood Biochemical Parameters in Rat with Chronic Glyphosate Intoxication and Therapeutic Use of C

Dmytro Nozdrenko, Olga Abramchuk, Svitlana Prylutska, Oksana Vygovska, Vasil Soroca, Kateryna Bogutska, Sergii Khrapatyi, Yuriy Prylutskyy, Peter Scharff, Uwe Ritter

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. CMolecules (Basel, Switzerland) · 2026
    Article
  2. Effects of Water-Soluble CMolecules (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. CInternational journal of molecular sciences · 2024
    Article
  6. СHeliyon · 2024
    Article
  7. Article
  8. Effect of CInternational journal of nanomedicine · 2024
    Article
  9. Review
  10. CHeliyon · 2022
    Article
  11. Article
  12. Effect of CLife (Basel, Switzerland) · 2022
    Article
  13. Carbon-Based Nanomaterials.International journal of molecular sciences · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Dmytro NozdrenkoDepartment of Biophysics and Medical Informatic, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
Olga AbramchukLesya Ukrainka Volyn National University, 43025 Lutsk, Ukraine.
Svitlana PrylutskaDepartment of Biophysics and Medical Informatic, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
Oksana VygovskaBogomolets National Medical University of Kyiv, 01601 Kyiv, Ukraine.
Vasil SorocaDepartment of Biophysics and Medical Informatic, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
Kateryna BogutskaDepartment of Biophysics and Medical Informatic, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.ORCID 0000-0003-0202-8042
Sergii KhrapatyiInterregional Academy of Personnel Management, 03039 Kyiv, Ukraine.
Yuriy PrylutskyyDepartment of Biophysics and Medical Informatic, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
Peter ScharffInstitute of Chemistry and Biotechnology, Technical University of Ilmenau, 98693 Ilmenau, Germany.
Uwe RitterInstitute of Chemistry and Biotechnology, Technical University of Ilmenau, 98693 Ilmenau, Germany.ORCID 0000-0002-9315-4863
Taras Shevchenko National University of Kyiv · UATechnische Universität Ilmenau · DEBogomolets National Medical University · UAInterregional Academy of Personnel Management · UALesya Ukrainka Volyn National University · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widespread use of glyphosate as a herbicide in agriculture can lead to the presence of its residues and metabolites in food for human consumption and thus pose a threat to human health. It has been found that glyphosate reduces energy metabolism in the brain, its amount increases in white muscle fibers. At the same time, the effect of chronic use of glyphosate on the dynamic properties of skeletal muscles remains practically unexplored. The selected biomechanical parameters (the integrated power of muscle contraction, the time of reaching the muscle contraction force its maximum value and the reduction of the force response by 50% and 25% of the initial values during stimulation) of muscle soleus contraction in rats, as well as blood biochemical parameters (the levels of creatinine, creatine phosphokinase, lactate, lactate dehydrogenase, thiobarbituric acid reactive substances, hydrogen peroxide, reduced glutathione and catalase) were analyzed after chronic glyphosate intoxication (oral administration at a dose of 10 μg/kg of animal weight) for 30 days. Water-soluble C

Indexed as

AnimalsAntioxidantsBiomarkersBiomechanical PhenomenaCatalaseFullerenesGlutathioneGlycineGlyphosateHydrogen PeroxideMuscle ContractionMuscle, SkeletalRatsThiobarbituric Acid Reactive SubstancesAntioxidantsBiomarkersCatalaseFullerenesGlutathioneGlycineGlyphosateHydrogen PeroxideThiobarbituric Acid Reactive Substancesbiomechanical parametersblood biochemical parametersC60 fullereneglyphosatemuscle soleus of rat

Identifiers

PMID34067082
PMCPMC8124638
OpenAlexW3158753484

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.