Evidence map›Paper›PMID 34067000›Full record

ArticleJournal of developmental biology2021

E-Cadherin/HMR-1 Membrane Enrichment Is Polarized by WAVE-Dependent Branched Actin.

Luigy Cordova-Burgos, Falshruti B Patel, Martha C Soto

Open access · goldAbstract read
In one paragraph

Article in Journal of developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. TheMolecular biology of the cell · 2026
    Article
  2. ThebioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. WAVE facilitates polarized E-cadherin transport.Molecular biology of the cell · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Luigy Cordova-BurgosDepartment of Pathology and Laboratory Medicine, Rutgers-RWJMS, Piscataway, NJ 08854, USA.
Falshruti B PatelDepartment of Pathology and Laboratory Medicine, Rutgers-RWJMS, Piscataway, NJ 08854, USA.
Martha C SotoDepartment of Pathology and Laboratory Medicine, Rutgers-RWJMS, Piscataway, NJ 08854, USA.
Rutgers, The State University of New Jersey · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Molecular mechanisms initiating cell migrations in Caonorhabditis elegansR01GM081670 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SOTO, MARTHA C. · 2009 to 2023
$4.3M
Laser Spinning Disc Confocal System for live-cell and live-organism microscopyS10OD010572 · OD · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SOTO, MARTHA C. · 2012 to 2012
$386k
NIGMS NIH HHS R01 GM081670NIH HHS 1S10OD010572NIH HHS GM081670NIH HHS P40 OD010440NIH HHS S10 OD010572
6 · The paper itself

Abstract

Polarized epithelial cells adhere to each other at apical junctions that connect to the apical F-actin belt. Regulated remodeling of apical junctions supports morphogenesis, while dysregulated remodeling promotes diseases such as cancer. We have documented that branched actin regulator, WAVE, and apical junction protein, Cadherin, assemble together in developing

Indexed as

apical junctionsbranched actinCadherinepithelial polarity

Identifiers

PMID34067000
PMCPMC8162361
OpenAlexW3159516198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.