Evidence map›Paper›PMID 34066987›Full record

ArticleCells2021

Codon Bias Can Determine Sorting of a Potassium Channel Protein.

Anja J Engel, Marina Kithil, Markus Langhans, Oliver Rauh, Matea Cartolano, James L Van Etten, Anna Moroni, Gerhard Thiel

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Identification and Characterization of Shaker KFrontiers in plant science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Anja J EngelMembrane Biophysics, Department of Biology, Technische Universität Darmstadt, 64287 Darmstadt, Germany.
Marina KithilMembrane Biophysics, Department of Biology, Technische Universität Darmstadt, 64287 Darmstadt, Germany.ORCID 0000-0003-2553-5629
Markus LanghansMembrane Biophysics, Department of Biology, Technische Universität Darmstadt, 64287 Darmstadt, Germany.ORCID 0000-0002-1117-5645
Oliver RauhMembrane Biophysics, Department of Biology, Technische Universität Darmstadt, 64287 Darmstadt, Germany.ORCID 0000-0003-1082-8656
Matea CartolanoMembrane Biophysics, Department of Biology, Technische Universität Darmstadt, 64287 Darmstadt, Germany.
James L Van EttenNebraska Center for Virology, Department of Plant Pathology, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.ORCID 0000-0002-5063-0049
Anna MoroniDepartment of Biosciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-1860-406X
Gerhard ThielMembrane Biophysics, Department of Biology, Technische Universität Darmstadt, 64287 Darmstadt, Germany.ORCID 0000-0002-2335-1351
Technische Universität Darmstadt · DEUniversity of Milan · ITUniversity of Nebraska–Lincoln · US

Funding

Deutsche Forschungsgemeinschaft SPP1926European Research Council 695078
6 · The paper itself

Abstract

Due to the redundancy of the genetic code most amino acids are encoded by multiple synonymous codons. It has been proposed that a biased frequency of synonymous codons can affect the function of proteins by modulating distinct steps in transcription, translation and folding. Here, we use two similar prototype K

Indexed as

Codon UsageGenetic CodeProtein BiosynthesisHumansPotassium ChannelsProtein TransportPotassium Channelscodon usagedual sortingeffect of synonymous codon exchangemembrane protein sorting

Identifiers

PMID34066987
PMCPMC8151079
OpenAlexW3163271696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.