Evidence map›Paper›PMID 34066952›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Burst of Corneal Dendritic Cells during Trastuzumab and Paclitaxel Treatment.

Katharina A Sterenczak, Nadine Stache, Sebastian Bohn, Stephan Allgeier, Bernd Köhler, Andreas Bartschat, Christian George, Rudolf F Guthoff, Oliver Stachs, Angrit Stachs

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Assessment of dynamic corneal nerve changes using static landmarks byQuantitative imaging in medicine and surgery · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Katharina A SterenczakDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0002-8122-4203
Nadine StacheDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0003-2919-8092
Sebastian BohnDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.
Stephan AllgeierInstitute for Automation and Applied Informatics, Karlsruhe Institute of Technology, 76021 Karlsruhe, Germany.ORCID 0000-0002-1218-448X
Bernd KöhlerInstitute for Automation and Applied Informatics, Karlsruhe Institute of Technology, 76021 Karlsruhe, Germany.ORCID 0000-0002-8124-2938
Andreas BartschatInstitute for Automation and Applied Informatics, Karlsruhe Institute of Technology, 76021 Karlsruhe, Germany.
Christian GeorgeDepartment of Obstetrics and Gynecology, University of Rostock, 18059 Rostock, Germany.
Rudolf F GuthoffDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.
Oliver StachsDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.
Angrit StachsDepartment of Obstetrics and Gynecology, University of Rostock, 18059 Rostock, Germany.
University of Rostock · DEKarlsruhe Institute of Technology · DE

Funding

German Federal Ministry of Education and Research Antifibrotix, 03VP06230German Research Foundation KO 5003/1-2, STA 543/6-2
6 · The paper itself

Abstract

During breast cancer therapy, paclitaxel and trastuzumab are both associated with adverse effects such as chemotherapy-induced peripheral neuropathy and other systemic side effects including ocular complications. Corneal nerves are considered part of the peripheral nervous system and can be imaged non-invasively by confocal laser scanning microscopy (CLSM) on the cellular level. Thus,

Indexed as

breast cancer therapydendritic cellsin vivo large-scale confocal laser scanning microscopyneuropathyocular complications

Identifiers

PMID34066952
PMCPMC8148560
OpenAlexW3157042335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.