Evidence map›Paper›PMID 34066917›Full record

ArticleHealthcare (Basel, Switzerland)2021

Ixekizumab May Improve Renal Function in Psoriasis.

Giuseppe Fabrizio Amoruso, Steven Paul Nisticò, Luigi Iannone, Emilio Russo, Giuseppe Rago, Cataldo Patruno, Luigi Bennardo

Open access · goldAbstract readCase Reports
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Use of Biological Drugs for Psoriasis: A Drug-Utilization Study Using Tuscan Administrative Databanks.International journal of environmental research and public health · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The Role of Podoplanin in Skin Diseases.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. The Role of Epigenetic Factors in Psoriasis.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giuseppe Fabrizio AmorusoUnit of Dermatology, Mariano Santo Hospital, 87100 Cosenza, Italy.
Steven Paul NisticòUnit of Dermatology, Department of Health Sciences, Magna Graecia University, Viale Europa SNC, 88100 Catanzaro, Italy.
Luigi IannoneUnit of Dermatology, Department of Health Sciences, Magna Graecia University, Viale Europa SNC, 88100 Catanzaro, Italy.
Emilio RussoUnit of Dermatology, Department of Health Sciences, Magna Graecia University, Viale Europa SNC, 88100 Catanzaro, Italy.
Giuseppe RagoCOVID Pneumology Unit, Ospedale di Rossano, 87067 Rossano, Italy.
Cataldo PatrunoUnit of Dermatology, Department of Health Sciences, Magna Graecia University, Viale Europa SNC, 88100 Catanzaro, Italy.ORCID 0000-0001-8661-2822
Luigi BennardoUnit of Dermatology, Department of Health Sciences, Magna Graecia University, Viale Europa SNC, 88100 Catanzaro, Italy.ORCID 0000-0002-0434-1027
Magna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPsoriasis is a chronic dermatological condition characterized by lesions on extensor surfaces, hands, feet, and genital areas. Chronic renal failure is often associated with metabolic syndrome and inflammatory conditions, such as psoriasis. CASE REPORT: In this paper, we report a patient with stage-three chronic renal failure that improved his renal condition after treatment with ixekizumab, an anti-IL17A drug used in the treatment of various cutaneous and rheumatological conditions.

conclusionsIL17A blockage may help to treat various autoimmune and inflammatory conditions, such as psoriasis, that may lead to renal impairment. Further investigation is necessary in order to prove the effectiveness of this drug in renal conditions.

Indexed as

chronic renal failureixekizumabpsoriasis

Identifiers

PMID34066917
PMCPMC8148436
OpenAlexW3159079116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.