Evidence map›Paper›PMID 34066916›Full record

ArticleCancers2021

Reply to Krupenko et al. Comment on "Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer

Seon-Hyeong Lee, Yoon Jeon, Joon-Hee Kang, Hyonchol Jang, Kyeong-Man Hong, Dongwan Hong, Ho Lee, Soo-Youl Kim

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Seon-Hyeong LeeDivision of Cancer Biology, Research Institute, National Cancer Center, Goyang 10408, Korea.ORCID 0000-0001-6492-1499
Yoon JeonDivision of Cancer Biology, Research Institute, National Cancer Center, Goyang 10408, Korea.
Joon-Hee KangDivision of Cancer Biology, Research Institute, National Cancer Center, Goyang 10408, Korea.
Hyonchol JangDivision of Cancer Biology, Research Institute, National Cancer Center, Goyang 10408, Korea.ORCID 0000-0003-1436-457X
Kyeong-Man HongDivision of Cancer Biology, Research Institute, National Cancer Center, Goyang 10408, Korea.
Dongwan HongDepartment of Medical Informatics, College of Medicine, Catholic University of Korea, Seoul 06591, Korea.
Ho LeeGraduate School of Cancer Science and Policy, National Cancer Center, Goyang 10408, Korea.ORCID 0000-0001-5573-742X
Soo-Youl KimDivision of Cancer Biology, Research Institute, National Cancer Center, Goyang 10408, Korea.
National Cancer Center · KRCatholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the Cancers paper, we observed the increase ALDH1L1 protein expression following oncogenesis, as well as a therapeutic effect, by deleting the

Identifiers

PMID34066916
PMCPMC8124425
OpenAlexW3158374420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.