Evidence map›Paper›PMID 34066912›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

Stereotactic Radiotherapy in the Treatment of Paraneoplastic Vasculitis in Oligometastatic Renal Cell Carcinoma.

Laura Burgess, Marissa Keenan, Alan Liang Zhou, Kiefer Lypka, Delvina Hasimja Saraqini, Jeff Yao, Samuel Martin, Christopher Morash, James Watterson, Christina Canil and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Laura BurgessDepartment of Radiology, Division of Radiation Oncology, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.ORCID 0000-0003-2664-0105
Marissa KeenanDepartment of Medicine, Division of Rheumatology, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.
Alan Liang ZhouDepartment of Medicine, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.ORCID 0000-0002-7525-5660
Kiefer LypkaDepartment of Medicine, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.
Delvina Hasimja SaraqiniDepartment of Medicine, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.ORCID 0000-0002-9084-6872
Jeff YaoDepartment of Surgery, Division of Urology, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.
Samuel MartinFaculty of Medicine, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.
Christopher MorashDepartment of Surgery, Division of Urology, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.
James WattersonDepartment of Surgery, Division of Urology, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.
Christina CanilDepartment of Medicine, Division of Medical Oncology, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.
Robert MacRaeDepartment of Radiology, Division of Radiation Oncology, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H8L6, Canada.
University of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 20% of renal cell carcinoma (RCC) is diagnosed because of paraneoplastic manifestations. RCC has been associated with a large variety of paraneoplastic syndromes (PNS), but it is rarely associated with PNS vasculitis. We present a case of a previously healthy male who presented with systemic vasculitis; bitemporal headaches, diplopia, polyarthritis, palpable purpura, tongue lesion, peri-orbital edema, scleritis, chondritis and constitutional symptoms. He was subsequently found to have oligometastatic RCC. Both his primary lesion and site of oligometastasis were treated with stereotactic radiotherapy (SBRT) and resulted in the resolution of his vasculitis, as well as sustained oncologic response. This is the first case to demonstrate that effective sustained treatment for PNS vasculitis due to oligometastatic RCC is possible with SBRT.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsParaneoplastic SyndromesRadiosurgeryVasculitisHumansMaleoligometastasesparaneoplastic syndromeparaneoplastic vasculitisrenal cell carcinoma (RCC)stereotactic radiotherapy (SBRT)

Identifiers

PMID34066912
PMCPMC8161761
OpenAlexW3159702995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.