Evidence map›Paper›PMID 34066886›Full record

ReviewMolecules (Basel, Switzerland)2021

Gravitational Influence on Human Living Systems and the Evolution of Species on Earth.

Konstantinos Adamopoulos, Dimitrios Koutsouris, Apostolos Zaravinos, George I Lambrou

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Bone Health in Space Flight: Incomplete Bone Mineral Density Convalescence at 1 Year Postmission Without Increased Fracture Risk.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Frontiers in immunology · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Life (Basel, Switzerland) · 2023
    Review
  18. Active matter in space.NPJ microgravity · 2022
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Konstantinos AdamopoulosSchool of Electrical and Computer Engineering, Biomedical Engineering Laboratory, National Technical University of Athens, Heroon Polytechneiou 9, Zografou, 15780 Athens, Greece.ORCID 0000-0001-6035-7990
Dimitrios KoutsourisSchool of Electrical and Computer Engineering, Biomedical Engineering Laboratory, National Technical University of Athens, Heroon Polytechneiou 9, Zografou, 15780 Athens, Greece.ORCID 0000-0003-1205-9918
Apostolos ZaravinosDepartment of Life Sciences, School of Sciences, European University Cyprus, 1516 Nicosia, Cyprus.ORCID 0000-0003-4625-5562
George I LambrouSchool of Electrical and Computer Engineering, Biomedical Engineering Laboratory, National Technical University of Athens, Heroon Polytechneiou 9, Zografou, 15780 Athens, Greece.ORCID 0000-0001-8389-1360
National Technical University of Athens · GREuropean University Cyprus · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gravity constituted the only constant environmental parameter, during the evolutionary period of living matter on Earth. However, whether gravity has affected the evolution of species, and its impact is still ongoing. The topic has not been investigated in depth, as this would require frequent and long-term experimentations in space or an environment of altered gravity. In addition, each organism should be studied throughout numerous generations to determine the profound biological changes in evolution. Here, we review the significant abnormalities presented in the cardiovascular, immune, vestibular and musculoskeletal systems, due to altered gravity conditions. We also review the impact that gravity played in the anatomy of snakes and amphibians, during their evolution. Overall, it appears that gravity does not only curve the space-time continuum but the biological continuum, as well.

Indexed as

Biological EvolutionCardiovascular Physiological PhenomenaHypergravityMusculoskeletal Physiological PhenomenaWeightlessnessAnimalsHumansImmune SystemSpace FlightThyroid GlandVestibule, Labyrinthastrobiologyevolutiongravitational biologyhypergravitymicrogravity

Identifiers

PMID34066886
PMCPMC8125950
OpenAlexW3161228039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.