Evidence map›Paper›PMID 34066885›Full record

ArticleCells2021

Profiling Complement System Components in Primary CNS Vasculitis.

Milani Deb-Chatterji, Christian W Keller, Simon Koch, Heinz Wiendl, Christian Gerloff, Tim Magnus, Jan D Lünemann

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Milani Deb-ChatterjiDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Christian W KellerDepartment of Neurology with Institute of Translational Neurology, University Hospital Münster, 48149 Münster, Germany.
Simon KochDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Heinz WiendlDepartment of Neurology with Institute of Translational Neurology, University Hospital Münster, 48149 Münster, Germany.
Christian GerloffDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Tim MagnusDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Jan D LünemannDepartment of Neurology with Institute of Translational Neurology, University Hospital Münster, 48149 Münster, Germany.
University Hospital Münster · DEUniversity Medical Center Hamburg-Eppendorf · DEUniversität Hamburg · DE

Funding

German Research Foundation MA 4375/5-1, 428778651German Research Foundation MA 4375/61, 428663564Swiss National Foundation 31003A-169664
6 · The paper itself

Abstract

Complement activation has been implicated in the pathogenesis of many vasculitic syndromes such as anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides. Using an array-based multiplex system, we simultaneously quantified serum and CSF levels of activated and regulatory complement system proteins in patients with primary CNS vasculitis (PACNS;

Indexed as

AdultAgedComplement ActivationComplement System ProteinsFemaleHumansMaleMiddle AgedVasculitis, Central Nervous SystemComplement System Proteinscomplement systemCSFneuroinflammationPACNSvasculitis

Identifiers

PMID34066885
PMCPMC8150982
OpenAlexW3162296111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.