ArticleMolecules (Basel, Switzerland)2021
Synthesis, Characterization, and Preliminary In Vitro Cytotoxic Evaluation of a Series of 2-Substituted Benzo [
Ozvaldo Linares-Anaya, Alcives Avila-Sorrosa, Francisco Díaz-Cedillo, Luis Ángel Gil-Ruiz, José Correa-Basurto, Domingo Salazar-Mendoza, Adrian L Orjuela, Jorge Alí-Torres, María Teresa Ramírez-Apan, David Morales-Morales
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Ozvaldo Linares-AnayaInstituto Politécnico Nacional, Departamento de Química Orgánica, Carpio y Plan de Ayala S/N, Escuela Nacional de Ciencias Biológicas, Colonia Santo Tomás, Ciudad de México 11340, Mexico.
Alcives Avila-SorrosaInstituto Politécnico Nacional, Departamento de Química Orgánica, Carpio y Plan de Ayala S/N, Escuela Nacional de Ciencias Biológicas, Colonia Santo Tomás, Ciudad de México 11340, Mexico.ORCID 0000-0001-7764-6676 Francisco Díaz-CedilloInstituto Politécnico Nacional, Departamento de Química Orgánica, Carpio y Plan de Ayala S/N, Escuela Nacional de Ciencias Biológicas, Colonia Santo Tomás, Ciudad de México 11340, Mexico.ORCID 0000-0001-9105-0617 Luis Ángel Gil-RuizInstituto Politécnico Nacional, Departamento de Química Orgánica, Carpio y Plan de Ayala S/N, Escuela Nacional de Ciencias Biológicas, Colonia Santo Tomás, Ciudad de México 11340, Mexico.
José Correa-BasurtoLaboratorio de Diseño y Desarrollo de Nuevos Fármacos e Innovación Biotecnológica, Instituto Politécnico Nacional, Escuela Superior de Medicina, Ciudad de México 11340, Mexico.ORCID 0000-0002-4973-5265 Domingo Salazar-MendozaCarretera a Acatlima, Huajuapan de León, Universidad Tecnológica de la Mixteca, Oaxaca 69000, Mexico.
Adrian L OrjuelaDepartamento de Química, Universidad Nacional de Colombia-Sede, Bogotá 111321, Colombia.
Jorge Alí-TorresDepartamento de Química, Universidad Nacional de Colombia-Sede, Bogotá 111321, Colombia.ORCID 0000-0003-1354-8713 María Teresa Ramírez-ApanInstituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Ciudad de México 04510, Mexico.ORCID 0000-0001-5123-5246 David Morales-MoralesInstituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Ciudad de México 04510, Mexico.ORCID 0000-0002-7984-1819 Funding
Consejo Nacional de Ciencia y Tecnología (México) CONACYT 62267Instituto Politécnico Nacional 2018500, 20190027, 20200028
6 · The paper itselfAbstract
Indexed as
Antineoplastic AgentsAzolesBinding SitesCell ProliferationCell SurvivalCytotoxinsDrug Screening Assays, AntitumorEstrogen Receptor alphaHumansMCF-7 CellsMolecular Docking SimulationMolecular StructurePC-3 CellsStructure-Activity RelationshipTamoxifenAntineoplastic AgentsAzolesCytotoxinsESR1 protein, humanEstrogen Receptor alphaTamoxifen2-substituted benzo [d] [1,3] azolesbreast cancerERα and GPERin vitro cytotoxicitymolecular docking
Identifiers
PMID34066820
PMCPMC8125891
What OpenQuestion holds
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LicenceCC BY
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