Evidence map›Paper›PMID 34066589›Full record

ReviewViruses2021

In Vivo Models to Study the Pathogenesis of Extra-Respiratory Complications of Influenza A Virus Infection.

Edwin Veldhuis Kroeze, Lisa Bauer, Valentina Caliendo, Debby van Riel

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Microorganisms · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Microbiology spectrum · 2023
    Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Edwin Veldhuis KroezeDepartment of Viroscience, Erasmus University Medical Center Rotterdam, 3015 CN Rotterdam, The Netherlands.ORCID 0000-0003-4951-1904
Lisa BauerDepartment of Viroscience, Erasmus University Medical Center Rotterdam, 3015 CN Rotterdam, The Netherlands.ORCID 0000-0002-9461-7284
Valentina CaliendoDepartment of Viroscience, Erasmus University Medical Center Rotterdam, 3015 CN Rotterdam, The Netherlands.
Debby van RielDepartment of Viroscience, Erasmus University Medical Center Rotterdam, 3015 CN Rotterdam, The Netherlands.ORCID 0000-0001-9753-3564
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal models are an inimitable method to study the systemic pathogenesis of virus-induced disease. Extra-respiratory complications of influenza A virus infections are not extensively studied even though they are often associated with severe disease and mortality. Here we review and recommend mammalian animal models that can be used to study extra-respiratory complications of the central nervous system and cardiovascular system as well as involvement of the eye, placenta, fetus, lacteal gland, liver, pancreas, intestinal tract, and lymphoid tissues during influenza A virus infections.

Indexed as

Disease Models, AnimalDisease SusceptibilityAnimalsCardiovascular DiseasesCentral Nervous System DiseasesHumansInfluenza A virusInfluenza, HumanOrgan Specificitycardiovascular diseasecentral nervous system diseasecranial nervesextra-respiratory diseaseinfluenzamammalian animal modelsolfactory nervepathogenesis

Identifiers

PMID34066589
PMCPMC8148586
OpenAlexW3159299871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.