Evidence map›Paper›PMID 34066336›Full record

ArticleViruses2021

Peste des Petits Ruminants Virus Infection at the Wildlife-Livestock Interface in the Greater Serengeti Ecosystem, 2015-2019.

Bryony A Jones, Mana Mahapatra, Daniel Mdetele, Julius Keyyu, Francis Gakuya, Ernest Eblate, Isaac Lekolool, Campaign Limo, Josephine N Ndiwa, Peter Hongo and 19 more

Open access · goldAbstract readHistorical Article
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 8 institutions in 6 countries.

Bryony A JonesRoyal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield AL9 7TA, UK.ORCID 0000-0003-4383-2504
Mana MahapatraThe Pirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.ORCID 0000-0002-3977-1465
Daniel MdeteleSACIDS Foundation for One Health, Sokoine University of Agriculture, P.O. Box 3297 Morogoro, Tanzania.
Julius KeyyuTanzania Wildlife Research Institute, P.O. Box 661 Arusha, Tanzania.
Francis GakuyaKenya Wildlife Service, P.O. Box 40241-00100 Nairobi, Kenya.
Ernest EblateTanzania Wildlife Research Institute, P.O. Box 661 Arusha, Tanzania.
Isaac LekoloolKenya Wildlife Service, P.O. Box 40241-00100 Nairobi, Kenya.
Campaign LimoKenya Wildlife Service, P.O. Box 40241-00100 Nairobi, Kenya.
Josephine N NdiwaPrivate Consultant, P.O. Box 42385-00100 Nairobi, Kenya.
Peter HongoKenya Wildlife Service, P.O. Box 40241-00100 Nairobi, Kenya.ORCID 0000-0002-7772-4045
Justin S WandaTanzania Wildlife Research Institute, P.O. Box 661 Arusha, Tanzania.
Ligge ShilindeTanzania Wildlife Research Institute, P.O. Box 661 Arusha, Tanzania.
Maulid MdakiTanzania Wildlife Research Institute, P.O. Box 661 Arusha, Tanzania.
Camilla BenfieldRoyal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield AL9 7TA, UK.
Krupali ParekhThe Pirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.
Martin Mayora NetoThe Pirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.
David NdeerehKenya Wildlife Service, P.O. Box 40241-00100 Nairobi, Kenya.
Gerald MisinzoSACIDS Foundation for One Health, Sokoine University of Agriculture, P.O. Box 3297 Morogoro, Tanzania.ORCID 0000-0003-1827-6403
Mariam R MakangeSACIDS Foundation for One Health, Sokoine University of Agriculture, P.O. Box 3297 Morogoro, Tanzania.
Alexandre CaronAnimals, Health, Territories, Risks and Ecosystem (ASTRE), University of Montpellier (UMR), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), National Research Institute for Agriculture, Food and the Environment (INRAE), F-34398 Montpellier, France.ORCID 0000-0002-5213-3273
Arnaud BatailleAnimals, Health, Territories, Risks and Ecosystem (ASTRE), University of Montpellier (UMR), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), National Research Institute for Agriculture, Food and the Environment (INRAE), F-34398 Montpellier, France.ORCID 0000-0002-3508-2144
Geneviève LibeauAnimals, Health, Territories, Risks and Ecosystem (ASTRE), University of Montpellier (UMR), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), National Research Institute for Agriculture, Food and the Environment (INRAE), F-34398 Montpellier, France.
Samia GuendouzAnimals, Health, Territories, Risks and Ecosystem (ASTRE), University of Montpellier (UMR), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), National Research Institute for Agriculture, Food and the Environment (INRAE), F-34398 Montpellier, France.
Emanuel S SwaiDirectorate of Veterinary Services, Ministry of Livestock and Fisheries, Mji wa Serikali Mtumba, Mtaa wa Ulinzi, P.O. Box 2870 Dodoma, Tanzania.ORCID 0000-0001-6273-7946
Obed NyasebwaDirectorate of Veterinary Services, Ministry of Livestock and Fisheries, Mji wa Serikali Mtumba, Mtaa wa Ulinzi, P.O. Box 2870 Dodoma, Tanzania.
Stephen L KoyieDepartment of Agriculture, Livestock and Fisheries, Narok County Government, P.O. Box 898-20500 Narok, Kenya.
Harry OyasDirectorate of Veterinary Services, Ministry of Agriculture, Livestock and Fisheries, P.O. Box 30028-00100 Nairobi, Kenya.
Satya ParidaThe Pirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.ORCID 0000-0001-8253-9461
Richard KockRoyal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield AL9 7TA, UK.ORCID 0000-0002-6561-3209
Kenya Wildlife Service · KETanzania Wildlife Research Institute · TZCentre de Coopération Internationale en Recherche Agronomique pour le Développement · FRThe Pirbright Institute · GBSouthern African Centre for Infectious Disease Surveillance · TZUniversity of London · GBMinistry of Livestock and Fisheries · TZMinistry of Agriculture Livestock and Fisheries · KE

Funding

Biotechnology and Biological Sciences Research Council BB/L013592/1Biotechnology and Biological Sciences Research Council BB/L013657/1
6 · The paper itself

Abstract

Peste des petits ruminants (PPR) is a viral disease of goats and sheep that occurs in Africa, the Middle East and Asia with a severe impact on livelihoods and livestock trade. Many wild artiodactyls are susceptible to PPR virus (PPRV) infection, and some outbreaks have threatened endangered wild populations. The role of wild species in PPRV epidemiology is unclear, which is a knowledge gap for the Global Strategy for the Control and Eradication of PPR. These studies aimed to investigate PPRV infection in wild artiodactyls in the Greater Serengeti and Amboseli ecosystems of Kenya and Tanzania. Out of 132 animals purposively sampled in 2015-2016, 19.7% were PPRV seropositive by ID Screen PPR competition enzyme-linked immunosorbent assay (cELISA; IDvet, France) from the following species: African buffalo, wildebeest, topi, kongoni, Grant's gazelle, impala, Thomson's gazelle, warthog and gerenuk, while waterbuck and lesser kudu were seronegative. In 2018-2019, a cross-sectional survey of randomly selected African buffalo and Grant's gazelle herds was conducted. The weighted estimate of PPRV seroprevalence was 12.0% out of 191 African buffalo and 1.1% out of 139 Grant's gazelles. All ocular and nasal swabs and faeces were negative by PPRV real-time reverse transcription-polymerase chain reaction (RT-qPCR). Investigations of a PPR-like disease in sheep and goats confirmed PPRV circulation in the area by rapid detection test and/or RT-qPCR. These results demonstrated serological evidence of PPRV infection in wild artiodactyl species at the wildlife-livestock interface in this ecosystem where PPRV is endemic in domestic small ruminants. Exposure to PPRV could be via spillover from infected small ruminants or from transmission between wild animals, while the relatively low seroprevalence suggests that sustained transmission is unlikely. Further studies of other major wild artiodactyls in this ecosystem are required, such as impala, Thomson's gazelle and wildebeest.

Indexed as

EcosystemAnimal DiseasesAnimalsAnimals, WildCross-Sectional StudiesDisease OutbreaksGeography, MedicalHistory, 21st CenturyKenyaLivestockPeste-des-Petits-RuminantsPeste-des-petits-ruminants virusPublic Health SurveillanceSeroepidemiologic StudiesTanzaniaepidemiologyeradicationgoatsKenyaPPRsheepsurveillanceTanzaniatransboundary animal diseasewild animals

Identifiers

PMID34066336
PMCPMC8148116
OpenAlexW3163275727

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.