Evidence map›Paper›PMID 34066290›Full record

ReviewMaterials (Basel, Switzerland)2021

Main 3D Manufacturing Techniques for Customized Bone Substitutes. A Systematic Review.

Javier Montero, Alicia Becerro, Beatriz Pardal-Peláez, Norberto Quispe-López, Juan-Francisco Blanco, Cristina Gómez-Polo

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Javier MonteroDepartment of Surgery, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0003-3936-6539
Alicia BecerroDepartment of Surgery, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-8725-9303
Beatriz Pardal-PeláezDepartment of Surgery, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain.
Norberto Quispe-LópezDepartment of Surgery, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain.
Juan-Francisco BlancoDepartment of Surgery, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain.
Cristina Gómez-PoloDepartment of Surgery, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinicians should be aware of the main methods and materials to face the challenge of bone shortage by manufacturing customized grafts, in order to repair defects. This study aims to carry out a bibliographic review of the existing methods to manufacture customized bone scaffolds through 3D technology and to identify their current situation based on the published papers. A literature search was carried out using "3D scaffold", "bone regeneration", "robocasting" and "3D printing" as descriptors. This search strategy was performed on PubMed (MEDLINE), Scopus and Cochrane Library, but also by hand search in relevant journals and throughout the selected papers. All the papers focusing on techniques for manufacturing customized bone scaffolds were reviewed. The 62 articles identified described 14 techniques (4 subtraction + 10 addition techniques). Scaffold fabrication techniques can be also be classified according to the time at which they are developed, into Conventional techniques and Solid Freeform Fabrication techniques. The conventional techniques are unable to control the architecture of the pore and the pore interconnection. However, current Solid Freeform Fabrication techniques allow individualizing and generating complex geometries of porosity. To conclude, currently SLA (Stereolithography), Robocasting and FDM (Fused deposition modeling) are promising options in customized bone regeneration.

Indexed as

3D printing3D scaffoldbone regenerationtissue engineering

Identifiers

PMID34066290
PMCPMC8152095

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.