ReviewNutrients2021
Dietary Management of Eosinophilic Esophagitis: Tailoring the Approach.
Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Dietary Approaches in Eosinophilic Esophagitis.Nutrients · 2026Review
- Dietary Therapy in Eosinophilic Esophagitis (EoE): A Practical Approach to Elimination.Current gastroenterology reports · 2026Review
- Evaluation of Functional T-Cell Assays That Predict Causal Allergens in Eosinophilic Esophagitis.Diagnostics (Basel, Switzerland) · 2026Article
- The Immune Architecture of Eosinophilic Esophagitis: Mechanisms, Therapeutic Targets, and Precision Management.ImmunoTargets and therapy · 2026Review
- Challenges in Dietary Therapy in Pediatric Eosinophilic Esophagitis (EoE)-A Narrative Review.Nutrients · 2025Review
- The Therapeutic Pipeline for Eosinophilic Esophagitis: Current Landscape and Future Directions.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Cow milk protein allergy mimics in infancy.World journal of clinical pediatrics · 2025Review
- Eosinophilic esophagitis and its association with food allergies: A United States national analysis 2016 to 2022.PloS one · 2025Article
- Observational
- Optimal Assessment, Treatment, and Monitoring of Adults with Eosinophilic Esophagitis: Strategies to Improve Outcomes.ImmunoTargets and therapy · 2024Review
- Current and Novel Therapies for Eosinophilic Gastrointestinal Diseases.International journal of molecular sciences · 2023Review
- A Practical Update on Pediatric Eosinophilic Esophagitis.Children (Basel, Switzerland) · 2023Review
- Non-Invasive and Minimally Invasive Biomarkers for the Management of Eosinophilic Esophagitis beyond Peak Eosinophil Counts: Filling the Gap in Clinical Practice.Diagnostics (Basel, Switzerland) · 2023Review
- Review
- Nutritional Pearls and Pitfalls of Gastrointestinal Diseases.Nutrients · 2023Article
- Dietary Strategies in Adult Patients with Eosinophilic Esophagitis: A State-of-the-Art Review.Nutrients · 2023Review
- Esophageal dysmotility in patients with eosinophilic esophagitis: pathogenesis, assessment tools, manometric characteristics, and clinical implications.Esophagus : official journal of the Japan Esophageal Society · 2023Review
- Management of Adult Patients with Gastrointestinal Symptoms from Food Hypersensitivity-Narrative Review.Journal of clinical medicine · 2022Review
- Eosinophilic esophagitis in children: Updates and practical aspects of management for allergists in a non-tertiary care private practice setup.Allergy and asthma proceedings · 2022Review
- Diet Therapy in Eosinophilic Esophagitis. Focus on a Personalized Approach.Frontiers in pediatrics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eosinophilic esophagitis (EoE) is a unique form of non-immunoglobulin E-mediated food allergy, restricted to the esophagus, characterized by esophageal eosinophil-predominant inflammation and dysfunction. The diagnosis requires an esophago-gastroduodenoscopy with esophageal biopsies demonstrating active eosinophilic inflammation with 15 or more eosinophils/high-power field, following the exclusion of alternative causes of eosinophilia. Food allergens trigger the disease, withdairy/milk, wheat/gluten, egg, soy/legumes, and seafood the most common. Therapeutic strategies comprise dietary restrictions, proton pump inhibitors, topical corticosteroids, biologic agents, and esophageal dilation when strictures are present. However, avoidance of trigger foods remains the only option targeting the cause, and not the effect, of the disease. Because EoE relapses when treatment is withdrawn, dietary therapy offers a long-term, drug-free alternative to patients who wish to remain off drugs and still be in remission. There are currently multiple dietary management strategies to choose from, each having its specific efficacy, advantages, and disadvantages that both clinicians and patients should acknowledge. In addition, dietary regimens should be tailored around each individual patient to increase the chance of tolerability and long-term adherence. In general, liquid elemental diets devoid of antigens and elimination diets restricting causative foods are valuable options. Designing diets on the basis of food allergy skin tests results is not reliable and should be avoided. This review summarizes the most recent knowledge regarding the clinical use of dietary measures in EoE. We discussed endpoints, rationale, advantages and disadvantages, and tailoring of diets, as well as currently available dietary regimens for EoE.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.