Evidence map›Paper›PMID 34066194›Full record

ArticleBrain sciences2021

Investigating the Relationship between Autistic Traits, Ruminative Thinking, and Suicidality in a Clinical Sample of Subjects with Bipolar Disorder and Borderline Personality Disorder.

Liliana Dell'Osso, Ivan Mirko Cremone, Giulia Amatori, Andrea Cappelli, Alessandro Cuomo, Stefano Barlati, Gabriele Massimetti, Antonio Vita, Andrea Fagiolini, Claudia Carmassi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Liliana Dell'OssoDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Ivan Mirko CremoneDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Giulia AmatoriDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Andrea CappelliDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Alessandro CuomoDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, Italy.
Stefano BarlatiDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0002-1784-3915
Gabriele MassimettiDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Antonio VitaDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0002-3621-6394
Andrea FagioliniDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, Italy.
Claudia CarmassiDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-3662-8073
Barbara CarpitaDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
University of Pisa · ITUniversity of Brescia · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Previous literature reported in both subjects with Borderline personality disorder (BPD) and Bipolar disorder (BD) higher levels of autistic traits, linked to a greater suicidality risk. The aim of this study was to evaluate and compare the presence of autistic traits in a sample of individuals with BD or BPD, with a specific focus on suicidality. (2) Methods: We recruited two clinical samples of subjects (BPD and BD) and a control group without a diagnosis according to DSM-5 (CTL). Subjects were assessed with the AdAS Spectrum, the RRS and, for evaluating suicidality, the MOODS-SR. (3) Results: The CTL group showed significantly lower scores of both BD and BPD on AdAS Spectrum, RRS, and suicidality scores. BPD subjects showed significantly lower scores than BD ones in most of AdAS Spectrum domain scores. Correlation and regression analyses highlighted specific patterns of association among AdAS Spectrum domains, RRS, and suicidality in each clinical group. (4) Conclusions: Both BPD and BD individuals show greater levels of autistic traits, which seem to be distributed in a continuum featuring the highest levels among BD subjects. In both disorders, higher autistic traits were linked to suicidal tendencies, although with different patterns of association between BD and BPD subjects.

Indexed as

autism spectrumautism spectrum disorderautistic traitsbipolar disorderborderline personality disordersuicide

Identifiers

PMID34066194
PMCPMC8151773
OpenAlexW3163345175

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.