ArticleDiagnostics (Basel, Switzerland)2021
Association of Early Renal Dysfunction with Lipid Profile Parameters among Hypertensives in Kazakhstan.
Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 7 citations in OpenAlex.
- Relationship between apolipoprotein A levels and chronic kidney disease stage 4-5 in Chinese type 2 diabetes participants.International urology and nephrology · 2026Article
- Novel anthropometric and lipid indices as predictors of chronic kidney disease: insights from a decade-long cohort study.Journal of health, population, and nutrition · 2025Article
- In-hospital and mid-term follow-up of low-density lipoprotein cholesterol and target-goal attainment among patients with acute cerebral infarction: a retrospective study.Lipids in health and disease · 2024Article
- Prevalence of chronic kidney disease in Kazakhstan: evidence from a national cross-sectional study.Scientific reports · 2023Article
- The association of apolipoprotein B with chronic kidney disease in the Chinese population.Frontiers in endocrinology · 2023Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
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Abstract
Dyslipidemia plays an essential role in chronic kidney disease (CKD). The role of lipids and lipoproteins in the early pre-disease state of CKD in hypertensive patients is still unclear. The study aimed to evaluate the relationship between early renal dysfunction and lipid profile parameters among hypertensive patients in Kazakhstan. From April 2015 to December 2016, 800 Kazakh males and females with primary hypertension who met the inclusion criteria were included in this cross-sectional study. Data were collected on socio-demographics, lifestyle parameters, family history of cardiovascular disease, and hypertension. Additionally, Dietary Quality Score (DQS), anthropometric data, and blood pressure were recorded. Laboratory blood measurements included eGFR (estimated glomerular filtration rate), lipid profile parameters such as Apolipoprotein B, A1, HDL-C, LDL-C, and TG. We found a linear relationship between early renal dysfunction and LDL-C, Apolipoprotein B, and Apolipoprotein B/A1 ratio, which was in all cases negative and small (
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