Evidence map›Paper›PMID 34066170›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Genetic and Epigenetic Alterations of

Gianluca Tedaldi, Chiara Molinari, Celina São José, Rita Barbosa-Matos, Ana André, Rita Danesi, Valentina Arcangeli, Mila Ravegnani, Luca Saragoni, Paolo Morgagni and 9 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  6. International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Gianluca TedaldiBiosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.ORCID 0000-0003-0540-6694
Chiara MolinariBiosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.ORCID 0000-0003-1011-5656
Celina São Joséi3S, Institute for Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0003-4292-3957
Rita Barbosa-Matosi3S, Institute for Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0003-0794-4912
Ana Andréi3S, Institute for Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.
Rita DanesiRomagna Cancer Registry, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.ORCID 0000-0002-6535-1608
Valentina ArcangeliRomagna Cancer Registry, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
Mila RavegnaniRomagna Cancer Registry, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
Luca SaragoniPathology Unit, Morgagni-Pierantoni Hospital, 47121 Forlì, Italy.ORCID 0000-0002-2137-9596
Paolo MorgagniDepartment of General Surgery, Morgagni-Pierantoni Hospital, 47121 Forlì, Italy.
Francesca RebuzziBiosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
Matteo CanaleBiosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.ORCID 0000-0002-9768-7149
Sara PignattaBiosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
Elisa FerracciLaboratory of Stem Cells and Cancer Genomics, University of Trento, 38123 Trento, Italy.
Giovanni MartinelliDepartment of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.ORCID 0000-0002-1025-4210
Guglielmina Nadia RanzaniDepartment of Biology and Biotechnology, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-3080-6473
Carla Oliveirai3S, Institute for Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0001-8340-2264
Daniele CalistriBiosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.ORCID 0000-0002-5064-2023
Paola UliviBiosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITUniversidade do Porto · PTOspedale G.B. Morgagni - L.Pierantoni · ITUniversity of Pavia · ITUniversity of Trento · IT

Funding

ERDF, POCI and FCT PTDC/BTM-TEC/30164/2017 (3DChroMe)FEDER - Fundo Europeu de Desenvolvimento Regional funds through the COMPETE 2020 - Operacional Programme for Competitiveness and Internationalization POCI-01-0145-FEDER-007274Norte Portugal Regional Programme (NORTE 2020) NORTE-01-0145-FEDER-000029Operacional Programme for Competitiveness and Internationalization (POCI), Portugal 2020 POCI-01-0145-FEDER-016390
6 · The paper itself

Abstract

E-cadherin is a key player in gastric cancer (GC) and germline alterations of

Indexed as

CDH1 geneDNA methylationgastric cancergenetic predispositionNext-Generation Sequencingregulatory regions

Identifiers

PMID34066170
PMCPMC8151134
OpenAlexW3161382338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.