Evidence map›Paper›PMID 34066039›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Galangin Resolves Cardiometabolic Disorders through Modulation of AdipoR1, COX-2, and NF-κB Expression in Rats Fed a High-Fat Diet.

Patoomporn Prasatthong, Sariya Meephat, Siwayu Rattanakanokchai, Juthamas Khamseekaew, Sarawoot Bunbupha, Parichat Prachaney, Putcharawipa Maneesai, Poungrat Pakdeechote

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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  11. Antioxidant Foods and Cardiometabolic Health.Antioxidants (Basel, Switzerland) · 2022
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  13. Propolis nanoemulsion extract from celebes stingless bee (Journal of oral biology and craniofacial research
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  14. Effect ofIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Patoomporn PrasatthongDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Sariya MeephatDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Siwayu RattanakanokchaiFaculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Juthamas KhamseekaewDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Sarawoot BunbuphaFaculty of Medicine, Mahasarakham University, Maha Sarakham 44000, Thailand.
Parichat PrachaneyDepartment of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Putcharawipa ManeesaiDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-0889-6211
Poungrat PakdeechoteDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Khon Kaen University · THMahasarakham University · TH

Funding

Fundamental Fund, Khon Kaen University, ThailandResearch Program, Khon Kaen University, Thailand
6 · The paper itself

Abstract

Galangin is a natural flavonoid. In this study, we evaluated whether galangin could alleviate signs of metabolic syndrome (MS) and cardiac abnormalities in rats receiving a high-fat (HF) diet. Male Sprague-Dawley rats were given an HF diet plus 15% fructose for four months, and they were fed with galangin (25 or 50 mg/kg), metformin (100 mg/kg), or a vehicle for the last four weeks. The MS rats exhibited signs of MS, hypertrophy of adipocytes, impaired liver function, and cardiac dysfunction and remodeling. These abnormalities were alleviated by galangin (

Indexed as

adiponectincardiac functiongalangininflammationmetabolic syndromeoxidative stress

Identifiers

PMID34066039
PMCPMC8150752
OpenAlexW3163606722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.