Evidence map›Paper›PMID 34065948›Full record

ReviewBiomolecules2021

The Pentose Phosphate Pathway in Yeasts-More Than a Poor Cousin of Glycolysis.

Laura-Katharina Bertels, Lucía Fernández Murillo, Jürgen J Heinisch

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 115 citations in OpenAlex.

  1. Review
  2. Construction of a globally modular recombinantSynthetic and systems biotechnology · 2026
    Article
  3. High-Throughput Analysis Reveals Stable Metabolome ofInternational journal of molecular sciences · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Physiological and Molecular Response Mechanisms ofInternational journal of molecular sciences · 2026
    Article
  12. Article
  13. Article
  14. Extracellular Phosphate Availability ImpactsJournal of fungi (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Engineering COInternational journal of molecular sciences · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Laura-Katharina BertelsDepartment of Genetics, Faculty of Biology/Chemistry, University of Osnabrück, Barbarastrasse 11, D-49076 Osnabrück, Germany.
Lucía Fernández MurilloDepartment of Genetics, Faculty of Biology/Chemistry, University of Osnabrück, Barbarastrasse 11, D-49076 Osnabrück, Germany.ORCID 0000-0001-9281-8296
Jürgen J HeinischDepartment of Genetics, Faculty of Biology/Chemistry, University of Osnabrück, Barbarastrasse 11, D-49076 Osnabrück, Germany.ORCID 0000-0003-4197-4285
Osnabrück University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pentose phosphate pathway (PPP) is a route that can work in parallel to glycolysis in glucose degradation in most living cells. It has a unidirectional oxidative part with glucose-6-phosphate dehydrogenase as a key enzyme generating NADPH, and a non-oxidative part involving the reversible transketolase and transaldolase reactions, which interchange PPP metabolites with glycolysis. While the oxidative branch is vital to cope with oxidative stress, the non-oxidative branch provides precursors for the synthesis of nucleic, fatty and aromatic amino acids. For glucose catabolism in the baker's yeast

Indexed as

AnimalsGlucoseGlycolysisHumansKluyveromycesOxidation-ReductionOxidative StressPentose Phosphate PathwaySaccharomyces cerevisiaeXyloseGlucoseXylosebioethanolcancercarbohydrate metabolismoxidative stressreduction power

Identifiers

PMID34065948
PMCPMC8151747
OpenAlexW3160252872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.