Evidence map›Paper›PMID 34065871›Full record

ArticleViruses2021

SARS-CoV-2 Persistent Viral Shedding in the Context of Hydroxychloroquine-Azithromycin Treatment.

Michel Drancourt, Sébastien Cortaredona, Cléa Melenotte, Sophie Amrane, Carole Eldin, Bernard La Scola, Philippe Parola, Matthieu Million, Jean-Christophe Lagier, Didier Raoult and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Michel DrancourtAix Marseille University, IRD, AP-HM, MEPHI, 13005 Marseille, France.
Sébastien CortaredonaIHU Méditerranée Infection, 13005 Marseille, France.ORCID 0000-0003-3523-7158
Cléa MelenotteAix Marseille University, IRD, AP-HM, MEPHI, 13005 Marseille, France.
Sophie AmraneAix Marseille University, IRD, AP-HM, MEPHI, 13005 Marseille, France.
Carole EldinIHU Méditerranée Infection, 13005 Marseille, France.
Bernard La ScolaAix Marseille University, IRD, AP-HM, MEPHI, 13005 Marseille, France.ORCID 0000-0001-8006-7704
Philippe ParolaIHU Méditerranée Infection, 13005 Marseille, France.
Matthieu MillionAix Marseille University, IRD, AP-HM, MEPHI, 13005 Marseille, France.
Jean-Christophe LagierAix Marseille University, IRD, AP-HM, MEPHI, 13005 Marseille, France.
Didier RaoultAix Marseille University, IRD, AP-HM, MEPHI, 13005 Marseille, France.
Philippe ColsonAix Marseille University, IRD, AP-HM, MEPHI, 13005 Marseille, France.ORCID 0000-0001-6285-0308
Aix-Marseille Université · FRMéditerranée Infection Foundation · FR

Funding

Agence Nationale de la Recherche Méditerranée infection 10-IAHU-03
6 · The paper itself

Abstract

SARS-CoV-2 nasopharyngeal shedding contributes to the spread of the COVID-19 epidemic. Among 3271 COVID-19 patients treated at the Hospital University Institute Méditerranée Infection, Marseille, France from 3 March to 27 April 2020, tested at least twice by qRT-PCR, the median SARS-CoV-2 nasopharyngeal shedding duration was 6 days (range 2-54 days). Compared with short shedders (qRT-PCR positivity < 10 days), 34 (1.04%) persistent shedders (qRT-PCR positivity ≥ 17 days; mean ± SD: 23.3 ± 3.8 days) were significantly older, with associated comorbidities, exhibiting lymphopenia, eosinopenia, increased D-dimer and increased troponin (

Indexed as

AdultAgedAzithromycinComorbidityCOVID-19COVID-19 Drug TreatmentDrug Therapy, CombinationFemaleFranceHospitalizationHumansHydroxychloroquineMaleMiddle AgedNasopharynxSARS-CoV-2AzithromycinHydroxychloroquineazithromycinCOVID-19culturehydroxychloroquineqRT-PCRSARS-CoV-2viral persistence

Identifiers

PMID34065871
PMCPMC8150993
OpenAlexW3160439640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.