ReviewNutrients2021
Boosting the Photoaged Skin: The Potential Role of Dietary Components.
Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 107 citations in OpenAlex.
- Oral consumption of Bonito fish-derived elastin peptide (VGPG ElastinSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Trial
- Trial
- Non-Invasive Imaging for the Evaluation of a New Oral Supplement in Skin Aging: A Case-Controlled Study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)Trial
- Article
- Melatonin Preserves Mitochondrial Redox Balance in UVB-Exposed Human Keratinocytes.Antioxidants (Basel, Switzerland) · 2026Article
- Article
- Chitosan-based nanozyme hydrogels: Advanced antioxidant and sustained-release systems for the prevention and treatment of skin photoaging.International journal of pharmaceutics: X · 2026Review
- Protective effect of young coconut water on MMP -1 levels and collagen fiber thickness in male Wistar rats exposed to UVB light exposure.Open veterinary journal · 2026Article
- Targeting Skin Aging at Multiple Fronts: Integrated In Silico and In Vitro Evidence of Antioxidant, Anti-Protease, and UVB-Protective Effects ofInternational journal of molecular sciences · 2026Article
- Dietary Supplementation withNutrients · 2026Article
- The Exposome in Melasma: A Comprehensive Review of Etiology, Mechanisms, and Implications for Management.Clinical, cosmetic and investigational dermatology · 2026Review
- Establishing an Improved Cellular Photoaging Model by Repeated UVA Exposure of Human Skin Fibroblasts.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2025Article
- Colla Corii Asini regulate collagen regeneration in UV exposure-induced skin photoaging in mice.Chinese medicine · 2025Article
- Low-Molecular-Weight Collagen Peptide Improves Skin Dehydration and Barrier Dysfunction in Human Dermal Fibrosis Cells and UVB-Exposed SKH-1 Hairless Mice.International journal of molecular sciences · 2025Article
- Platelet-rich plasma alleviates skin photoaging by activating autophagy and inhibiting inflammasome formation.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Role of Nutritional Elements in Skin Homeostasis: A Review.Biomolecules · 2025Review
- Potential Role of Dietary Antioxidants During Skin Aging.Food science & nutrition · 2025Review
- Synthetic and Natural Agents Targeting Advanced Glycation End-Products for Skin Anti-Aging: A Comprehensive Review of Experimental and Clinical Studies.Antioxidants (Basel, Switzerland) · 2025Review
- Reversing Oxinflammation Associated with Glycative Stress and Formation of Advanced Glycation End Products with a Dietary Supplement Containing Rosemary Extract.The Journal of clinical and aesthetic dermatology · 2025Article
- A Single-center, Double-blinded, Randomized, Placebo-controlled Trial Evaluating the Safety and Efficacy of a Dietary Supplement Containing Rosemary Extract on Visible Facial Skin Quality.The Journal of clinical and aesthetic dermatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Skin photoaging is mainly induced by ultraviolet (UV) irradiation and its manifestations include dry skin, coarse wrinkle, irregular pigmentation, and loss of skin elasticity. Dietary supplementation of nutraceuticals with therapeutic and preventive effects against skin photoaging has recently received increasing attention. This article aims to review the research progress in the cellular and molecular mechanisms of UV-induced skin photoaging. Subsequently, the beneficial effects of dietary components on skin photoaging are discussed. The photoaging process and the underlying mechanisms are complex. Matrix metalloproteinases, transforming growth factors, skin adipose tissue, inflammation, oxidative stress, nuclear and mitochondrial DNA, telomeres, microRNA, advanced glycation end products, the hypothalamic-pituitary-adrenal axis, and transient receptor potential cation channel V are key regulators that drive the photoaging-associated changes in skin. Meanwhile, mounting evidence from animal models and clinical trials suggests that various food-derived components attenuate the development and symptoms of skin photoaging. The major mechanisms of these dietary components to alleviate skin photoaging include the maintenance of skin moisture and extracellular matrix content, regulation of specific signaling pathways involved in the synthesis and degradation of the extracellular matrix, and antioxidant capacity. Taken together, the ingestion of food-derived functional components could be an attractive strategy to prevent skin photoaging damage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.