Evidence map›Paper›PMID 34065698›Full record

Trial reportInternational journal of environmental research and public health2021

Virtual Reality-Based Cognitive Stimulation on People with Mild to Moderate Dementia due to Alzheimer's Disease: A Pilot Randomized Controlled Trial.

Jorge Oliveira, Pedro Gamito, Teresa Souto, Rita Conde, Maria Ferreira, Tatiana Corotnean, Adriano Fernandes, Henrique Silva, Teresa Neto

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 18 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 18 syntheses or guidelines pooled it, 124 citations in OpenAlex.

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  4. Digital Cognitive Rehabilitation Platforms for Older Adults in Portugal: A Systematic Review.International journal of environmental research and public health · 2026
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  14. Cognitive rehabilitation for people with mild to moderate dementia.The Cochrane database of systematic reviews · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jorge OliveiraDigital Human-Environment Interaction Lab-HEI-Lab, Lusófona University, 1749-024 Lisboa, Portugal.ORCID 0000-0002-3467-4981
Pedro GamitoDigital Human-Environment Interaction Lab-HEI-Lab, Lusófona University, 1749-024 Lisboa, Portugal.
Teresa SoutoDigital Human-Environment Interaction Lab-HEI-Lab, Lusófona University, 1749-024 Lisboa, Portugal.
Rita CondeDigital Human-Environment Interaction Lab-HEI-Lab, Lusófona University, 1749-024 Lisboa, Portugal.
Maria FerreiraDigital Human-Environment Interaction Lab-HEI-Lab, Lusófona University, 1749-024 Lisboa, Portugal.ORCID 0000-0003-0045-200X
Tatiana CorotneanDepartment of Psychology, Lusófona University, 1749-024 Lisboa, Portugal.
Adriano FernandesSanta Casa da Misericórdia da Amadora-SCMA, 2610-143 Amadora, Portugal.
Henrique SilvaSanta Casa da Misericórdia da Amadora-SCMA, 2610-143 Amadora, Portugal.
Teresa NetoSanta Casa da Misericórdia da Amadora-SCMA, 2610-143 Amadora, Portugal.
Universidade Lusófona · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of ecologically oriented approaches with virtual reality (VR) depicting instrumental activities of daily living (IADL) is a promising approach for interventions on acquired brain injuries. However, the results of such an approach on dementia caused by Alzheimer's disease (AD) are still lacking. This research reports on a pilot randomized controlled trial that aimed to explore the effect of a cognitive stimulation reproducing several IADL in VR on people with mild-to-moderate dementia caused by AD. Patients were recruited from residential care homes of Santa Casa da Misericórdia da Amadora (SCMA), which is a relevant nonprofit social and healthcare provider in Portugal. This intervention lasted two months, with a total of 10 sessions (two sessions/week). A neuropsychological assessment was carried out at the baseline and follow-up using established neuropsychological instruments for assessing memory, attention, and executive functions. The sample consisted of 17 patients of both genders randomly assigned to the experimental and control groups. The preliminary results suggested an improvement in overall cognitive function in the experimental group, with an effect size corresponding to a large effect in global cognition, which suggests that this approach is effective for neurocognitive stimulation in older adults with dementia, contributing to maintaining cognitive function in AD.

Indexed as

Alzheimer DiseaseVirtual RealityActivities of Daily LivingAgedCognitionFemaleHumansMalePilot ProjectsPortugalagingAlzheimer’s diseasecomputerized cognitive stimulationdementiaecological validityvirtual reality

Identifiers

PMID34065698
PMCPMC8156930
OpenAlexW3160035995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.