ArticleBrain sciences2021
Assessment of a Reliable Fractional Anisotropy Cutoff in Tractography of the Corticospinal Tract for Neurosurgical Patients.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Longitudinal spatial changes of the contralesional corticospinal tract in high-grade glioma: a within-patient DTI tractography study.Journal of neuro-oncology · 2026Article
- Mills-Nithi algorithm for navigated transcranial magnetic stimulation motor mapping in healthy subjects and brain tumor patients.Clinical neurophysiology practice · 2026Article
- DTI fiber-tracking parameters adjacent to gliomas: the role of tract irregularity value in operative planning, resection, and outcome.Journal of neuro-oncology · 2025Observational
- Radiomic white matter parameters of functional integrity of the corticospinal tract in high-grade glioma.Scientific reports · 2024Article
- Review
- Usefulness and Limits of Tractography for Surgery in the Precentral Gyrus-A Case Report.Clinics and practice · 2022Article
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Authors and funding
8 authors.
Funding
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Abstract
backgroundTractography has become a standard technique for planning neurosurgical operations in the past decades. This technique relies on diffusion magnetic resonance imaging. The cutoff value for the fractional anisotropy (FA) has an important role in avoiding false-positive and false-negative results. However, there is a wide variation in FA cutoff values.
methodsWe analyzed a prospective cohort of 14 patients (six males and eight females, 50.1 ± 4.0 years old) with intracerebral tumors that were mostly gliomas. Magnetic resonance imaging (MRI) was obtained within 7 days before and within 7 days after surgery with T1 and diffusion tensor image (DTI) sequences. We, then, reconstructed the corticospinal tract (CST) in all patients and extracted the FA values within the resulting volume.
resultsThe mean FA in all CSTs was 0.4406 ± 0.0003 with the fifth percentile at 0.1454. FA values in right-hemispheric CSTs were lower (
conclusionAn FA cutoff value of 0.15 appears to be reasonable for neurosurgical patients and may shorten the tractography workflow. However, infiltrated fiber bundles must trigger vigilance and may require lower cutoffs.
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