Evidence map›Paper›PMID 34065652›Full record

ArticleBiomolecules2021

Evaluating Mechanisms of IDH1 Regulation through Site-Specific Acetylation Mimics.

Joi Weeks, Alexandra I Strom, Vinnie Widjaja, Sati Alexander, Dahra K Pucher, Christal D Sohl

Open access · goldAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Atlas of lysine acetylation in the mouse.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joi WeeksDepartment of Chemistry and Biochemistry, San Diego State University, San Diego, CA 92182, USA.
Alexandra I StromDepartment of Chemistry and Biochemistry, San Diego State University, San Diego, CA 92182, USA.
Vinnie WidjajaDepartment of Chemistry and Biochemistry, San Diego State University, San Diego, CA 92182, USA.ORCID 0000-0002-3190-5633
Sati AlexanderDepartment of Chemistry and Biochemistry, San Diego State University, San Diego, CA 92182, USA.
Dahra K PucherDepartment of Chemistry and Biochemistry, San Diego State University, San Diego, CA 92182, USA.ORCID 0000-0002-1935-9289
Christal D SohlDepartment of Chemistry and Biochemistry, San Diego State University, San Diego, CA 92182, USA.ORCID 0000-0002-8048-0205
San Diego State University · USUniversity of Southern California · US

Funding

Research Education CoreU54CA132384 · NCI · SAN DIEGO STATE UNIVERSITY · PI CRIPPS, RICHARD MATTHEW, CROWE, SHEILA E. · 2008 to 2022
$20.7M
Isocitrate dehydrogenase (IDH) mutations as drivers of organelle stress and dysfunction"R35GM137773 · NIGMS · SAN DIEGO STATE UNIVERSITY · PI Christal Dyane Sohl · 2020 to 2026
$2.7M
American Cancer Society 133484-RSG-19-075-01-TBENCI NIH HHS U54 CA132384NIGMS NIH HHS R35 GM137773NIH HHS 5R25GM058906NIH HHS 5T34GM008303NIH HHS R35 GM137773
6 · The paper itself

Abstract

Isocitrate dehydrogenase (IDH1) catalyzes the reversible NADP

Indexed as

MutationProtein Processing, Post-TranslationalAcetylationBrain NeoplasmsComputer SimulationGlioblastomaGliomaHumansIsocitrate DehydrogenaseMutagenesis, Site-DirectedRecombinant ProteinsStructure-Activity RelationshipIDH1 protein, humanIsocitrate DehydrogenaseRecombinant ProteinsacetylationIDH1kineticspost-translational modification

Identifiers

PMID34065652
PMCPMC8157008
OpenAlexW3160443796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.