Evidence map›Paper›PMID 34065629›Full record

ReviewMolecules (Basel, Switzerland)2021

Visual pH Sensors: From a Chemical Perspective to New Bioengineered Materials.

Luigi Di Costanzo, Barbara Panunzi

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
  7. Synthesis and characterization of a nitrophenol disubstituted BODIPY halochromic probe.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  8. Review
  9. Article
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  11. Review
  12. Review
  13. Reliable and accurate prediction of basic pKJournal of cheminformatics · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Ratiometric pH-ResponsiveAnalytical chemistry · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Luigi Di CostanzoDepartment of Agricultural Sciences, University of Naples Federico II, 100, 80055 Portici, Italy.ORCID 0000-0002-4795-2573
Barbara PanunziDepartment of Agricultural Sciences, University of Naples Federico II, 100, 80055 Portici, Italy.ORCID 0000-0001-9253-0794
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many human activities and cellular functions depend upon precise pH values, and pH monitoring is considered a fundamental task. Colorimetric and fluorescence sensors for pH measurements are chemical and biochemical tools able to sense protons and produce a visible signal. These pH sensors are gaining widespread attention as non-destructive tools, visible to the human eye, that are capable of a real-time and in-situ response. Optical "visual" sensors are expanding researchers' interests in many chemical contexts and are routinely used for biological, environmental, and medical applications. In this review we provide an overview of trending colorimetric, fluorescent, or dual-mode responsive visual pH sensors. These sensors include molecular synthetic organic sensors, metal organic frameworks (MOF), engineered sensing nanomaterials, and bioengineered sensors. We review different typological chemical entities of visual pH sensors, three-dimensional structures, and signaling mechanisms for pH sensing and applications; developed in the past five years. The progression of this review from simple organic molecules to biological macromolecules seeks to benefit beginners and scientists embarking on a project of pH sensing development, who needs background information and a quick update on advances in the field. Lessons learned from these tools will aid pH determination projects and provide new ways of thinking for cell bioimaging or other cutting-edge in vivo applications.

Indexed as

BioengineeringBiosensing TechniquesColorimetryFluorescenceHumansHydrogen-Ion ConcentrationMetal-Organic FrameworksNanostructuresMetal-Organic FrameworkscolorimetricfluorescenceGFPMOFoptical sensorspH

Identifiers

PMID34065629
PMCPMC8156760
OpenAlexW3162099068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.