Evidence map›Paper›PMID 34065599›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Outcomes of Esophageal Cancer after Esophagectomy in the Era of Early Injection Laryngoplasty.

Tuan-Jen Fang, Yu-Cheng Pei, Yi-An Lu, Hsiu-Feng Chung, Hui-Chen Chiang, Hsueh-Yu Li, Alice M K Wong

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tuan-Jen FangDepartment of Otolaryngology Head & Neck Surgery, Chang Gung Memorial Hospital at Linkou, 5 Fushing St., Taoyuan 333, Taiwan.ORCID 0000-0002-7805-3458
Yu-Cheng PeiSchool of Medicine, Chang Gung University, 259 Wen-Hwa 1st Road, Taoyuan 333, Taiwan.
Yi-An LuDepartment of Otolaryngology Head & Neck Surgery, Chang Gung Memorial Hospital at Linkou, 5 Fushing St., Taoyuan 333, Taiwan.
Hsiu-Feng ChungDepartment of Otolaryngology Head & Neck Surgery, Chang Gung Memorial Hospital at Linkou, 5 Fushing St., Taoyuan 333, Taiwan.
Hui-Chen ChiangGraduate School of Management, Ming Chun University, 250 Zhong Shan N Rd., Sec.5, Taipei 111, Taiwan.
Hsueh-Yu LiDepartment of Otolaryngology Head & Neck Surgery, Chang Gung Memorial Hospital at Linkou, 5 Fushing St., Taoyuan 333, Taiwan.
Alice M K WongSchool of Medicine, Chang Gung University, 259 Wen-Hwa 1st Road, Taoyuan 333, Taiwan.
Chang Gung University · TWLinkou Chang Gung Memorial Hospital · TWMing Chuan University · TW

Funding

Chang Gung Medical Foundation CMRPG310212Ministry of Science and Technology MOST 107-2314-B-182A-084-MY3
6 · The paper itself

Abstract

(1) Background: severe weight loss was reported to be related to unilateral vocal fold paralysis (UVFP) after esophagectomy and could thus impair survival. Concomitant radical lymph node dissection along the recurrent laryngeal nerve during esophageal cancer surgery is controversial, as it might induce UVFP. Early intervention for esophagectomy-related UVFP by administering intracordal injections of temporal agents has recently become popular. This study investigated the survival outcomes of esophagectomy for esophageal squamous cell carcinoma (ESCC) after the introduction of early injection laryngoplasty (EIL). (2) Methods: a retrospective review of patients with ESCC after curative-intent esophagectomy was conducted in a tertiary referral medical center. The necessity of EIL with hyaluronic acid was comprehensively discussed for all symptomatic UVFP patients. The survival outcomes and related risk factors of ESCC were evaluated. (3) Results: among the cohort of 358 consecutive patients who underwent esophagectomy for ESCC, 42 (11.7%) showed postsurgical UVFP. Twenty-nine of them received office-based EIL. After EIL, the glottal gap area, maximum phonation time and voice outcome survey showed significant improvement at one, three and six months measurements. The number of lymph nodes in the resected specimen was higher in those with UVFP than in those without UVFP (30.1 ± 15.7 vs. 24.6 ± 12.7,

Indexed as

esophageal canceresophagectomyinjection laryngoplastysurvivalunilateral vocal fold paralysis

Identifiers

PMID34065599
PMCPMC8160664
OpenAlexW3163690651

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.