Evidence map›Paper›PMID 34065524›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Lasting Effects of Low to Non-Lethal Radiation Exposure during Late Gestation on Offspring's Cardiac Metabolism and Oxidative Stress.

Ashley S Nemec-Bakk, Sarah Niccoli, Caitlund Davidson, Danika Roy, Lisa Stoa, Shayenthiran Sreetharan, Alain Simard, Douglas R Boreham, Joanna Y Wilson, T C Tai and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Ashley S Nemec-BakkDepartment of Science and Environmental Studies, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.
Sarah NiccoliDepartment of Biology, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.ORCID 0000-0001-5832-1980
Caitlund DavidsonDepartment of Biology, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.
Danika RoyNorthern Ontario School of Medicine, Laurentian University, Sudbury, ON P3E 2C6, Canada.
Lisa StoaDepartment of Biology, McMaster University, Hamilton, ON L8S 4L8, Canada.
Shayenthiran SreetharanDepartment of Biology, McMaster University, Hamilton, ON L8S 4L8, Canada.
Alain SimardNorthern Ontario School of Medicine, Laurentian University, Sudbury, ON P3E 2C6, Canada.ORCID 0000-0002-3499-6235
Douglas R BorehamNorthern Ontario School of Medicine, Laurentian University, Sudbury, ON P3E 2C6, Canada.
Joanna Y WilsonDepartment of Biology, McMaster University, Hamilton, ON L8S 4L8, Canada.ORCID 0000-0003-4245-1304
T C TaiNorthern Ontario School of Medicine, Laurentian University, Sudbury, ON P3E 2C6, Canada.
Simon J LeesDepartment of Biology, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.
Neelam KhaperDepartment of Biology, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.
Laurentian University · CALakehead University · CAMcMaster University · CA

Funding

Natural Sciences and Engineering Research Council of Canada CRDPJ 494077-16Nuclear Innovation Institute NII
6 · The paper itself

Abstract

Ionizing radiation (IR) is known to cause fetal programming, but the physiological effects of low-dose IR are not fully understood. This study examined the effect of low (50 mGy) to non-lethal (300 and 1000 mGy) radiation exposure during late gestation on cardiac metabolism and oxidative stress in adult offspring. Pregnant C57BL/6J mice were exposed to 50, 300, or 1000 mGy of gamma radiation or Sham irradiation on gestational day 15. Sixteen weeks after birth,

Indexed as

antioxidantscardiaclow-dose radiationoxidative stress

Identifiers

PMID34065524
PMCPMC8160807
OpenAlexW3163896888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.