Evidence map›Paper›PMID 34065446›Full record

ArticleBiomedicines2021

The Insulin Receptor: A Potential Target of Amarogentin Isolated from

Lihong Cheng, Hiroyuki Osada, Tianyan Xing, Minoru Yoshida, Lan Xiang, Jianhua Qi

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. International journal of molecular sciences · 2024
    Article
  3. Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lihong ChengCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-2522-4831
Hiroyuki OsadaChemical Biology Research Group, RIKEN Center for Sustainable Resource Science, Wako-shi, Saitama 351-0198, Japan.
Tianyan XingSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.ORCID 0000-0002-0479-056X
Minoru YoshidaChemical Genomics Research Group, RIKEN Center for Sustainable Resource Science, Wako-shi, Saitama 351-0198, Japan.ORCID 0000-0002-4376-5674
Lan XiangCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Jianhua QiCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Zhejiang University · CNRIKEN Center for Sustainable Resource Science · JPHubei University of Chinese Medicine · CN

Funding

National Key R&D Program of China 2017YFE0117200, 2019YFE0100700National Natural Science Foundation of China 21877098, 21661140001
6 · The paper itself

Abstract

Amarogentin (AMA) is a secoiridoid glycoside isolated from the traditional Chinese medicine,

Indexed as

agingAlzheimer’s diseaseinsulin receptorneurodegenerative diseasetarget identification

Identifiers

PMID34065446
PMCPMC8160887
OpenAlexW3164472767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.