Evidence map›Paper›PMID 34065390›Full record

ArticleInternational journal of molecular sciences2021

MAT2A Localization and Its Independently Prognostic Relevance in Breast Cancer Patients.

Pei-Yi Chu, Hsing-Ju Wu, Shin-Mae Wang, Po-Ming Chen, Feng-Yao Tang, En-Pei Isabel Chiang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. A novel role of secreted methionine adenosyltransferase α2 in colorectal liver metastases.Journal of experimental & clinical cancer research : CR · 2025
    Article
  4. Article
  5. The role of BCancer & metabolism · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Breast Cancer: From Pathophysiology to Novel Therapeutic Approaches 2.0.International journal of molecular sciences · 2023
    Article
  13. Article
  14. Article
  15. Ketogenic Diet Consumption Inhibited Mitochondrial One-Carbon Metabolism.International journal of molecular sciences · 2022
    Article
  16. Downregulation of Methionine Cycle GenesInternational journal of molecular sciences · 2022
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Pei-Yi ChuSchool of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242, Taiwan.ORCID 0000-0001-7336-2465
Hsing-Ju WuDepartment of Biology, National Changhua University of Education, Changhua 500, Taiwan.
Shin-Mae WangDepartment of General Surgery, Show Chwan Memorial Hospital, Changhua 500, Taiwan.
Po-Ming ChenResearch Assistant Center, Show Chwan Memorial Hospital, Changhua 500, Taiwan.
Feng-Yao TangBiomedical Science Laboratory, Department of Nutrition, China Medical University, Taichung 40402, Taiwan.
En-Pei Isabel ChiangDepartment of Food Science and Biotechnology, National Chung Hsing University, Taichung 40402, Taiwan.ORCID 0000-0002-0158-0962
Chang Bing Show Chwan Memorial Hospital · TWNational Chung Hsing University · TWChina Medical University · TWFu Jen Catholic University · TW

Funding

Ministry of Science Research and Technology 107-2320-B005-003-MY3
6 · The paper itself

Abstract

(1) Background: methionine cycle is not only essential for cancer cell proliferation but is also critical for metabolic reprogramming, a cancer hallmark. Hepatic and extrahepatic tissues methionine adenosyltransferases (MATs) are products of two genes, MAT1A and MAT2A that catalyze the formation of

Indexed as

AdultAgedAged, 80 and overBreast NeoplasmsCell ProliferationFemaleHumansLymph NodesMethionineMethionine AdenosyltransferaseMiddle AgedNeoplasm MetastasisPrognosisMAT2A protein, humanMethionineMethionine Adenosyltransferasebreast cancerGNMTMAT1AMAT2Aprognosissubcellular localization

Identifiers

PMID34065390
PMCPMC8161225
OpenAlexW3161102958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.