Evidence map›Paper›PMID 34065380›Full record

Trial reportNutrients2021

Postprandial Lipid Metabolism in Normolipidemic Subjects and Patients with Mild to Moderate Hypertriglyceridemia: Effects of Test Meals Containing Saturated Fatty Acids, Mono-Unsaturated Fatty Acids, or Medium-Chain Fatty Acids.

Alexander Folwaczny, Elisa Waldmann, Julia Altenhofer, Kerstin Henze, Klaus G Parhofer

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05539742 (Comparison of the Effect of Medium-Chain Fatty Acids and Long-Chain Fatty Acids on Postprandial Appetite and Lipemia), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05539742 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparison of the Effect of Medium-Chain Fatty Acids and Long-Chain Fatty Acids on Postprandial Appetite and Lipemia

TypeinterventionalSponsorUniversity of JordanRan2022 to 2022Enrolled26ConditionsLipemiaArmsCoconut oil, Palm oil
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alexander FolwacznyDepartment of Internal Medicine 4, Ludwig-Maximilians University Munich, 81377 Munich, Germany.
Elisa WaldmannDepartment of Internal Medicine 4, Ludwig-Maximilians University Munich, 81377 Munich, Germany.
Julia AltenhoferDepartment of Internal Medicine 4, Ludwig-Maximilians University Munich, 81377 Munich, Germany.
Kerstin HenzeDepartment of Internal Medicine 4, Ludwig-Maximilians University Munich, 81377 Munich, Germany.
Klaus G ParhoferDepartment of Internal Medicine 4, Ludwig-Maximilians University Munich, 81377 Munich, Germany.ORCID 0000-0001-9873-0412
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fasting and postprandial hypertriglyceridemia are causal risk factors for atherosclerosis. The prevalence of hypertriglyceridemia is approximately 25-30% and most hypertriglyceridemic patients suffer from mild to moderate hypertriglyceridemia. Data regarding dietary interventions on postprandial triglyceride metabolism of mildly to moderately hypertriglyceridemic patients is, however, sparse. In a randomized controlled trial, eight mildly hypertriglyceridemic patients and five healthy, normolipidemic controls received three separate standardized fat-meals containing either saturated fatty acids (SFA), mono-unsaturated fatty acids (MUFA), or medium-chain fatty acids (MCFA) in a randomized order. Fasting and postprandial lipid parameters were determined over a 10 h period and the (incremental) area under the curve (AUC/iAUC) for plasma triglycerides and other parameters were determined. MCFA do not lead to a significant elevation of postprandial total plasma triglycerides and other triglyceride parameters, while both SFA (patients:

Indexed as

AdultDietary FatsFastingFatty AcidsFatty Acids, MonounsaturatedFemaleHumansHypertriglyceridemiaLipid MetabolismLipidsMaleMealsMiddle AgedPostprandial PeriodTriglyceridesDietary FatsFatty AcidsFatty Acids, MonounsaturatedLipidsTriglyceridesfatty acidshyperlipidemiahypertriglyceridemiaMCTmedium chain triglycerides

Identifiers

PMID34065380
PMCPMC8160756
OpenAlexW3161702568

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.