Evidence map›Paper›PMID 34065259›Full record

ArticleMembranes2021

Simulations on Simple Models of Connexin Hemichannels Indicate That Ca

Felipe Villanelo, Jorge Carrasco, Joaquin Jensen-Flores, Jose Antonio Garate, Tomas Perez-Acle

Abstract read
In one paragraph

Article in Membranes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Calcium Regulation of Connexin Hemichannels.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Felipe VillaneloComputational Biology Laboratory, Fundación Ciencia & Vida, Zañartu 1482, Ñuñoa, Santiago 7780132, Chile.ORCID 0000-0001-7901-172X
Jorge CarrascoComputational Biology Laboratory, Fundación Ciencia & Vida, Zañartu 1482, Ñuñoa, Santiago 7780132, Chile.
Joaquin Jensen-FloresComputational Biology Laboratory, Fundación Ciencia & Vida, Zañartu 1482, Ñuñoa, Santiago 7780132, Chile.
Jose Antonio GarateCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, Valparaíso 2360102, Chile.
Tomas Perez-AcleComputational Biology Laboratory, Fundación Ciencia & Vida, Zañartu 1482, Ñuñoa, Santiago 7780132, Chile.

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 1211045Iniciativa Científica Milenio P09-022-FPrograma de Apoyo a Centros con Financiamiento Basal AFB170004
6 · The paper itself

Abstract

Connexin hemichannels allow the unspecific but regulated interchange of molecules from ions to second messenger and ATP, between the eukariotic cell and its extracellular space. The transport of ions and water through hemichannels is important for physiological functions and also in the progression of several pathological conditions. Extracellular Ca

Indexed as

calcium-bindingconnexinhemichannelsimulation

Identifiers

PMID34065259
PMCPMC8161212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.