Evidence map›Paper›PMID 34065225›Full record

ArticleInternational journal of molecular sciences2021

Oxonium Ion Guided Analysis of Quantitative Proteomics Data Reveals Site-Specific

Martina Pirro, Yassene Mohammed, Arnoud H de Ru, George M C Janssen, Rayman T N Tjokrodirijo, Katarina Madunić, Manfred Wuhrer, Peter A van Veelen, Paul J Hensbergen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Martina PirroCenter for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0001-9562-2395
Yassene MohammedCenter for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0003-3265-3332
Arnoud H de RuCenter for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
George M C JanssenCenter for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Rayman T N TjokrodirijoCenter for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Katarina MadunićCenter for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Manfred WuhrerCenter for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-0814-4995
Peter A van VeelenCenter for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Paul J HensbergenCenter for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-3193-5445
Leiden University Medical Center · NLUniversity of Victoria · CA

Funding

Horizon 2020 676421Nederlandse Organisatie voor Wetenschappelijk Onderzoek 91116004
6 · The paper itself

Abstract

Developments in mass spectrometry (MS)-based analyses of glycoproteins have been important to study changes in glycosylation related to disease. Recently, the characteristic pattern of oxonium ions in glycopeptide fragmentation spectra had been used to assign different sets of glycopeptides. In particular, this was helpful to discriminate between

Indexed as

Cell Line, TumorGlycopeptidesGlycoproteinsGlycosylationHCT116 CellsHT29 CellsHumansIonsMucoproteinsOncogene ProteinsOnium CompoundsProteomicsTandem Mass SpectrometryAGR2 protein, humanGlycopeptidesGlycoproteinshydronium ionIonsMucoproteinsOncogene ProteinsOnium CompoundsAGR2colorectal cancerglycoproteomicsLC−MS/MSO-glycosylationoxonium ionTMT labeling

Identifiers

PMID34065225
PMCPMC8160981
OpenAlexW3161595622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.